h-pen
Generic Name
Penicillin V Potassium
Manufacturer
X Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| h pen 250 mg tablet | ৳ 1.35 | N/A |
Description
Overview of the medicine
H-pen 250 mg Tablet is a penicillin antibiotic used to treat a variety of bacterial infections.
Uses & Indications
Dosage
Adults
250-500 mg every 6-8 hours, depending on the severity of the infection.
Elderly
Generally adult dosage, but renal function should be considered.
Renal_impairment
Dosage adjustment may be required in severe renal impairment.
How to Take
Take orally, preferably on an empty stomach (1 hour before or 2 hours after meals) to maximize absorption.
Mechanism of Action
It works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death.
Pharmacokinetics
Onset
30-60 minutes
Excretion
Primarily excreted unchanged by the kidneys.
Half life
Approximately 30-60 minutes
Absorption
Rapidly and well absorbed from the gastrointestinal tract. Absorption may be reduced by food.
Metabolism
Minimally metabolized; some partial metabolism occurs.
Side Effects
Contraindications
- Known hypersensitivity to penicillin or other beta-lactam antibiotics.
- History of severe allergic reaction to penicillin.
Drug Interactions
Methotrexate
Penicillin V may decrease renal clearance of methotrexate, leading to increased methotrexate levels and potential toxicity.
Tetracyclines
May reduce the bactericidal effect of penicillin V.
Oral contraceptives
Some reports suggest penicillin V may reduce the effectiveness of oral contraceptives, though evidence is limited.
Storage
Store below 25°C in a dry and cool place. Protect from light and moisture.
Overdose
In case of overdose, symptoms are generally gastrointestinal upset. Management includes symptomatic treatment and supportive care.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation, but consultation with a doctor is advised.
Side Effects
Contraindications
- Known hypersensitivity to penicillin or other beta-lactam antibiotics.
- History of severe allergic reaction to penicillin.
Drug Interactions
Methotrexate
Penicillin V may decrease renal clearance of methotrexate, leading to increased methotrexate levels and potential toxicity.
Tetracyclines
May reduce the bactericidal effect of penicillin V.
Oral contraceptives
Some reports suggest penicillin V may reduce the effectiveness of oral contraceptives, though evidence is limited.
Storage
Store below 25°C in a dry and cool place. Protect from light and moisture.
Overdose
In case of overdose, symptoms are generally gastrointestinal upset. Management includes symptomatic treatment and supportive care.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation, but consultation with a doctor is advised.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2 years from the date of manufacture.
Availability
Pharmacies, Hospitals
Approval Status
Approved
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have demonstrated the efficacy of Penicillin V Potassium in various bacterial infections, confirming its long-standing role as a cornerstone antibiotic.
Lab Monitoring
- Renal function tests (for prolonged therapy or in patients with pre-existing renal impairment).
- Complete blood count (rarely for prolonged therapy).
Doctor Notes
- Always inquire about patient's history of allergies, especially to penicillin or other beta-lactam antibiotics, before prescribing.
- Advise patients on the importance of completing the full course of treatment.
- Monitor for signs of allergic reactions, such as rash or difficulty breathing.
Patient Guidelines
- Complete the full course of medication as prescribed by your doctor, even if symptoms improve.
- Do not share your medication with others.
- Take with food if stomach upset occurs, but generally empty stomach is preferred.
Missed Dose Advice
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
H-pen 250 mg Tablet usually does not affect the ability to drive or operate heavy machinery.
Lifestyle Advice
- Get adequate rest to aid recovery.
- Stay hydrated by drinking plenty of fluids.
- Maintain good hygiene to prevent further spread of infection.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.