H-Trimazole
Generic Name
H-Trimazole 1% w/w Cream
Manufacturer
Alpha Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| h trimazole 1 1 cream | ৳ 35.63 | N/A |
Description
Overview of the medicine
H-Trimazole 1% w/w Cream is a broad-spectrum antifungal medication used to treat various fungal infections of the skin, such as athlete's foot, jock itch, ringworm, and other candidal infections. It works by stopping the growth of fungi.
Uses & Indications
Dosage
Adults
Apply a thin layer of cream to the affected area(s) and surrounding skin, gently rubbing in, once or twice daily. Continue treatment for at least 2 weeks after symptoms disappear.
Elderly
No special dosage adjustment is required for elderly patients.
Renal_impairment
No dosage adjustment is required for patients with renal impairment.
How to Take
For external use only. Wash and dry the affected area thoroughly before applying the cream. Apply a thin layer and gently rub it in. Wash hands thoroughly after application.
Mechanism of Action
H-Trimazole interferes with the biosynthesis of ergosterol, an essential component of fungal cell membranes. This leads to structural and functional impairment of the fungal cytoplasmic membrane, resulting in leakage of cellular contents and eventual fungal cell death.
Pharmacokinetics
Onset
Symptomatic relief usually begins within a few days of treatment.
Excretion
Primarily excreted via the bile.
Half life
Not well-defined for topical application due to minimal systemic absorption.
Absorption
Minimal systemic absorption occurs after topical application, with most of the drug remaining in the stratum corneum and epidermis.
Metabolism
Any systemically absorbed drug is rapidly metabolized in the liver.
Side Effects
Contraindications
- Known hypersensitivity to H-Trimazole or any component of the cream.
- Not for ophthalmic or oral use.
Drug Interactions
Topical Corticosteroids
Avoid concurrent use unless directed by a doctor, as corticosteroids may suppress local immune responses.
Other Topical Antifungals
Avoid concurrent use of other topical antifungals unless advised by a healthcare professional.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Overdose from topical application is unlikely due to minimal systemic absorption. In case of accidental ingestion, seek medical advice immediately. Management is supportive.
Pregnancy & Lactation
Use during pregnancy and lactation only if the potential benefit outweighs the potential risk. Consult a doctor before use.
Side Effects
Contraindications
- Known hypersensitivity to H-Trimazole or any component of the cream.
- Not for ophthalmic or oral use.
Drug Interactions
Topical Corticosteroids
Avoid concurrent use unless directed by a doctor, as corticosteroids may suppress local immune responses.
Other Topical Antifungals
Avoid concurrent use of other topical antifungals unless advised by a healthcare professional.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Overdose from topical application is unlikely due to minimal systemic absorption. In case of accidental ingestion, seek medical advice immediately. Management is supportive.
Pregnancy & Lactation
Use during pregnancy and lactation only if the potential benefit outweighs the potential risk. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Pharmacies, drugstores
Approval Status
Approved
Patent Status
Expired
Clinical Trials
Efficacy and safety have been established in multiple clinical trials for the treatment of various dermatophyte and candidal infections.
Lab Monitoring
- Not required for typical topical use.
Doctor Notes
- Advise patients on proper hygiene practices to prevent recurrence.
- Emphasize completing the full course of treatment to ensure eradication of the fungus.
- Monitor for signs of allergic reactions or worsening of symptoms.
Patient Guidelines
- Clean and dry the affected area thoroughly before applying the cream.
- Apply a thin layer and gently rub it in.
- Wash your hands before and after applying the cream.
- Avoid contact with eyes, mouth, and other mucous membranes.
- Do not cover the treated area with occlusive dressings unless advised by a doctor.
- Complete the full course of treatment, even if symptoms improve.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.
Driving Precautions
H-Trimazole 1% w/w Cream has no known effect on the ability to drive or operate machinery.
Lifestyle Advice
- Keep the affected skin area clean and dry.
- Wear loose-fitting, breathable clothing.
- Avoid sharing towels, clothing, or personal items to prevent spreading the infection.
- Maintain good personal hygiene.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.