handirub
Generic Name
Chlorhexidine Gluconate 0.5% w/v & Ethyl Alcohol 70% v/v Hand Rub
Manufacturer
Generic Health Co.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| handirub 05 70 hand rub | ৳ 40.00 | N/A |
Description
Overview of the medicine
Handirub 0.5-70 Hand Rub is an alcohol-based antiseptic solution containing Chlorhexidine Gluconate and Ethyl Alcohol. It is used for rapid and effective hand disinfection to kill germs and prevent the spread of infection.
Uses & Indications
Dosage
Adults
For hygienic hand antisepsis, apply 3-5 ml to clean, dry hands and rub thoroughly until dry (approx. 30 seconds). For surgical hand preparation, follow institutional protocol, typically involving multiple applications for a longer duration.
Elderly
Same as adults.
Renal_impairment
No dosage adjustment required as systemic absorption is minimal.
How to Take
For external use only. Apply undiluted to clean, dry hands. Rub hands together, covering all surfaces, until completely dry. Do not rinse with water.
Mechanism of Action
Ethyl alcohol denatures proteins and solubilizes lipids, leading to cellular damage and death of microorganisms. Chlorhexidine Gluconate disrupts bacterial cell membranes, causing leakage of intracellular components and bacterial cell death. The combination provides a broad spectrum of antimicrobial activity.
Pharmacokinetics
Onset
Rapid (within seconds for alcohol)
Excretion
Not applicable for topical, non-systemic product
Half life
Not applicable for topical, non-systemic product
Absorption
Minimal systemic absorption from topical application. Primarily acts on the skin surface.
Metabolism
Not applicable for topical, non-systemic product
Side Effects
Contraindications
- Hypersensitivity to chlorhexidine, alcohol, or any other component of the formulation.
- Should not be used on open wounds, damaged skin, or mucous membranes.
- Avoid contact with eyes, ears, and mouth.
Drug Interactions
Soaps and Anionic Agents
Anionic agents (e.g., certain soaps, detergents) can neutralize the action of chlorhexidine. Rinse hands thoroughly if soap was used prior to application.
Other topical preparations
Avoid concurrent use with other topical antiseptic products unless advised by a healthcare professional.
Storage
Store below 30°C in a cool, dry place. Keep away from direct sunlight, heat, and flames. Keep container tightly closed. Do not freeze.
Overdose
Topical overdose is unlikely to cause systemic effects. Accidental ingestion may lead to alcohol poisoning, requiring immediate medical attention. Symptoms may include nausea, vomiting, dizziness, drowsiness, and in severe cases, respiratory depression or coma.
Pregnancy & Lactation
Considered safe for use during pregnancy and lactation when applied topically as directed, due to minimal systemic absorption.
Side Effects
Contraindications
- Hypersensitivity to chlorhexidine, alcohol, or any other component of the formulation.
- Should not be used on open wounds, damaged skin, or mucous membranes.
- Avoid contact with eyes, ears, and mouth.
Drug Interactions
Soaps and Anionic Agents
Anionic agents (e.g., certain soaps, detergents) can neutralize the action of chlorhexidine. Rinse hands thoroughly if soap was used prior to application.
Other topical preparations
Avoid concurrent use with other topical antiseptic products unless advised by a healthcare professional.
Storage
Store below 30°C in a cool, dry place. Keep away from direct sunlight, heat, and flames. Keep container tightly closed. Do not freeze.
Overdose
Topical overdose is unlikely to cause systemic effects. Accidental ingestion may lead to alcohol poisoning, requiring immediate medical attention. Symptoms may include nausea, vomiting, dizziness, drowsiness, and in severe cases, respiratory depression or coma.
Pregnancy & Lactation
Considered safe for use during pregnancy and lactation when applied topically as directed, due to minimal systemic absorption.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Pharmacies, supermarkets, online stores
Approval Status
Over-the-Counter (OTC)
Patent Status
Generic / No active patent
WHO Essential Medicine
YesClinical Trials
The efficacy of alcohol-based hand rubs and chlorhexidine formulations is well-established through numerous clinical studies and guidelines (e.g., WHO guidelines for hand hygiene). Specific trials for this brand typically focus on formulation stability and skin tolerability rather than primary efficacy.
Lab Monitoring
- No specific lab monitoring is required for routine topical use.
Doctor Notes
- Educate patients on proper hand hygiene technique.
- Advise patients on the importance of moisturizing hands if dryness occurs.
- Emphasize that it is for external use only and to avoid ingestion.
Patient Guidelines
- Read the label carefully before use.
- Ensure hands are clean and dry before application.
- Apply sufficient amount to cover all hand surfaces.
- Rub hands thoroughly until dry; do not wipe or rinse.
- Avoid contact with eyes, ears, mouth, and broken skin.
- Keep out of reach of children.
- Flammable: Keep away from fire or flame.
Missed Dose Advice
This product is used on-demand. There is no concept of a 'missed dose'. Use as needed for hand hygiene.
Driving Precautions
None. This product does not affect the ability to drive or operate machinery.
Lifestyle Advice
- Regular hand hygiene is essential for preventing the spread of infections.
- Use moisturizers if skin dryness occurs with frequent use.
- Maintain good personal hygiene practices.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.