Hartman
Generic Name
Ringer's Lactate Solution
Manufacturer
Various manufacturers globally (e.g., Beximco Pharma, Square Pharma in Bangladesh)
Country
Global
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| hartman injection | ৳ 71.30 | N/A |
Description
Overview of the medicine
Hartman's Injection, also known as Ringer's Lactate Solution, is an intravenous fluid commonly used for fluid and electrolyte replenishment. It contains sodium, potassium, calcium, chloride, and lactate, which is metabolized to bicarbonate, helping to correct metabolic acidosis.
Uses & Indications
Dosage
Adults
Dosage is individualized based on patient's age, weight, clinical condition, and fluid/electrolyte requirements, usually 1000-3000 mL/24 hours.
Elderly
Same as adults, but monitor for fluid overload and renal function.
Renal_impairment
Administer with caution, monitor fluid and electrolyte balance closely. May require reduced dosage or alternative solutions.
How to Take
Administered via intravenous infusion. The rate of administration should be adjusted according to the patient's fluid requirements and clinical response.
Mechanism of Action
Provides water and electrolytes (Na+, K+, Ca2+, Cl-) to restore fluid balance and replenish lost electrolytes. Lactate is metabolized in the liver to bicarbonate, which helps to correct or prevent acidosis.
Pharmacokinetics
Onset
Immediate upon administration.
Excretion
Electrolytes and water are excreted primarily by the kidneys.
Half life
The half-life of lactate is approximately 20-30 minutes, but fluid and electrolyte balance correction is continuous as long as infusion persists.
Absorption
Administered intravenously, directly into the bloodstream.
Metabolism
Lactate is metabolized primarily in the liver to bicarbonate.
Side Effects
Contraindications
- Severe congestive heart failure
- Severe renal impairment (anuria, oliguria)
- Hypernatremia, hyperkalemia, hypercalcemia
- Severe metabolic alkalosis
- Lactic acidosis (though lactate is a precursor, severe lactic acidosis may impair metabolism)
Drug Interactions
Corticosteroids
May increase sodium and fluid retention.
Digitalis glycosides
Increased risk of digitalis toxicity with hypercalcemia (calcium in solution).
Diuretics (potassium-sparing)
Risk of hyperkalemia due to potassium content.
Drugs that alkalinize urine (e.g., sodium bicarbonate)
May alter elimination of renally excreted drugs.
Storage
Store at room temperature (below 30°C). Do not freeze. Protect from light.
Overdose
Overdose can lead to fluid overload, electrolyte imbalances (hypernatremia, hyperkalemia, hypercalcemia), and metabolic alkalosis. Management involves discontinuing infusion, administering diuretics if needed, and correcting electrolyte imbalances.
Pregnancy & Lactation
Considered safe for use during pregnancy and lactation when indicated for fluid and electrolyte replacement, but consult a physician.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years, depending on the manufacturer and packaging.
Availability
Hospitals, Clinics, Pharmacies
Approval Status
Generally approved worldwide, commonly available.
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
As a well-established and old solution, extensive clinical trials have been conducted over decades, demonstrating its efficacy and safety for fluid resuscitation and electrolyte balance. Newer trials often compare it with other IV fluids (e.g., normal saline) regarding specific patient outcomes.
Lab Monitoring
- Serum electrolytes (Na+, K+, Ca2+, Cl-)
- Renal function (BUN, creatinine)
- Fluid balance (input/output)
- Acid-base status (arterial blood gas)
Doctor Notes
- Careful monitoring of fluid balance, serum electrolytes, and acid-base status is crucial.
- Administer with caution in patients with hyperkalemia or severe renal impairment.
- Lactate metabolism to bicarbonate may be impaired in severe liver disease or shock.
Patient Guidelines
- This medication is administered by healthcare professionals.
- Report any discomfort or adverse reactions during infusion.
- Inform your doctor about any pre-existing medical conditions, especially heart or kidney problems.
Missed Dose Advice
As this is usually administered in a hospital setting under medical supervision, a missed dose is unlikely. If an infusion is interrupted, the medical team will reassess and restart as necessary.
Driving Precautions
No specific precautions directly related to the drug itself, but underlying conditions requiring IV fluids might impair driving ability.
Lifestyle Advice
- Maintain adequate hydration as advised by your doctor.
- Follow dietary recommendations, especially if on a restricted diet due to other conditions.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.