Heel-guard
Generic Name
Urea
Manufacturer
Reputable Pharmaceutical Co. Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| heel guard 25 w cream | ৳ 150.00 | N/A |
Description
Overview of the medicine
Heel-guard 25 W Cream is a topical preparation containing 25% w/w Urea, used for treating cracked heels, dry and rough skin, and other hyperkeratotic conditions. It works by moisturizing and softening the skin, aiding in the removal of dead skin cells.
Uses & Indications
Dosage
Adults
Apply to affected areas twice daily, or as directed by a physician.
Elderly
No specific dosage adjustment required for elderly patients.
Renal_impairment
No specific dosage adjustment required as systemic absorption is minimal.
How to Take
For external use only. Wash and dry the affected area before applying a thin layer of cream. Gently rub until absorbed. Wash hands after application.
Mechanism of Action
Urea is a keratolytic and emollient agent. As a keratolytic, it helps to loosen and shed dead skin cells from the skin's surface by breaking down the intercellular matrix. As an emollient, it hydrates the skin by attracting and holding water, increasing moisture content and improving skin elasticity.
Pharmacokinetics
Onset
Visible effects within days to a week of regular use.
Excretion
Primarily local action. Any absorbed urea is excreted renally.
Half life
Not significant due to minimal systemic absorption.
Absorption
Minimal systemic absorption after topical application to intact skin. Absorption may increase with damaged skin.
Metabolism
Not extensively metabolized systemically due to minimal absorption. If absorbed, follows endogenous urea metabolic pathways.
Side Effects
Contraindications
- Hypersensitivity to Urea or any component of the cream
- Broken, inflamed, or bleeding skin (consult doctor)
Drug Interactions
No significant drug interactions reported
Systemic interactions are unlikely due to minimal absorption.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.
Overdose
Overdose with topical application is unlikely. Excessive application may cause local irritation. In case of accidental ingestion, seek medical advice.
Pregnancy & Lactation
Generally considered safe for topical use during pregnancy and lactation, but consult a healthcare professional before use.
Side Effects
Contraindications
- Hypersensitivity to Urea or any component of the cream
- Broken, inflamed, or bleeding skin (consult doctor)
Drug Interactions
No significant drug interactions reported
Systemic interactions are unlikely due to minimal absorption.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.
Overdose
Overdose with topical application is unlikely. Excessive application may cause local irritation. In case of accidental ingestion, seek medical advice.
Pregnancy & Lactation
Generally considered safe for topical use during pregnancy and lactation, but consult a healthcare professional before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from manufacturing date.
Availability
Pharmacies nationwide
Approval Status
Approved by regulatory authorities
Patent Status
Generic
WHO Essential Medicine
YesClinical Trials
Urea's efficacy for hyperkeratotic and dry skin conditions is well-established through numerous clinical studies.
Lab Monitoring
- Not typically required for topical urea.
Doctor Notes
- Advise patients on proper application technique and hygiene.
- Differentiate from lower concentration urea creams used for general moisturization.
- Monitor for signs of excessive irritation, especially in sensitive patients.
Patient Guidelines
- For external use only.
- Avoid contact with eyes, nose, mouth, and mucous membranes.
- Do not apply to open wounds or severely broken skin.
- Discontinue use if irritation persists and consult a doctor.
Missed Dose Advice
If a dose is missed, apply it as soon as remembered. Do not apply a double dose to make up for a missed one.
Driving Precautions
No known effects on ability to drive or operate machinery.
Lifestyle Advice
- Maintain good foot hygiene.
- Wear comfortable, well-fitting shoes.
- Drink plenty of water to keep skin hydrated.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.