Helo
Generic Name
Pantoprazole Sodium
Manufacturer
Hypothetical Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| helo 20 mg injection | ৳ 1,200.00 | N/A |
Description
Overview of the medicine
Helo 20 mg Injection contains Pantoprazole Sodium, a proton pump inhibitor, used to treat conditions caused by excessive stomach acid production.
Uses & Indications
Dosage
Adults
20 mg once daily by intravenous infusion, typically for up to 7 days, or as directed by physician. Dosage may be increased to 40 mg once daily for more severe conditions.
Elderly
No specific dose adjustment is generally required, but caution is advised in those with severe hepatic impairment.
Renal_impairment
No dose adjustment is necessary for patients with renal impairment.
How to Take
Administer intravenously over 2 to 15 minutes, typically once daily. Reconstitute lyophilized powder with appropriate solvent as per manufacturer's instructions.
Mechanism of Action
Irreversibly binds to and inactivates the H+/K+-ATPase proton pump in parietal cells, thereby inhibiting gastric acid secretion.
Pharmacokinetics
Onset
Within 15-30 minutes
Excretion
Primarily via urine (approx. 80%) and feces (approx. 20%)
Half life
Approximately 1 hour (terminal half-life)
Absorption
Rapidly absorbed after intravenous administration, achieving peak plasma concentration quickly.
Metabolism
Extensively metabolized in the liver via CYP2C19 and CYP3A4 enzymes.
Side Effects
Contraindications
- •Hypersensitivity to pantoprazole or any component of the formulation
- •Hypersensitivity to substituted benzimidazoles
Drug Interactions
Warfarin
Increased INR and bleeding risk.
Clopidogrel
Potential for reduced antiplatelet effect (clinical significance debated).
Methotrexate
Increased methotrexate levels, especially high doses.
Atazanavir/Nelfinavir
Reduced absorption, decreased antiviral efficacy.
Storage
Store below 30°C, protect from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Symptoms may include confusion, blurred vision, abdominal pain. Treatment is symptomatic and supportive; no specific antidote for pantoprazole overdose.
Pregnancy & Lactation
Use in pregnancy only if clearly needed and the potential benefits outweigh the risks. Excreted in breast milk, use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months when stored as recommended. Reconstituted solution is stable for a limited time.
Availability
Pharmacies, Hospitals
Approval Status
Approved by regulatory authorities
Patent Status
Expired
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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