Hexisol
Generic Name
Chlorhexidine Gluconate 0.5% w/v & Ethyl Alcohol 70% v/v Hand Rub
Manufacturer
Acme Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| hexisol 05 70 hand rub | ৳ 55.00 | N/A |
Description
Overview of the medicine
Hexisol-05-70-Hand-Rub is an antiseptic solution formulated for rapid and effective hand disinfection. It contains Chlorhexidine Gluconate and Ethyl Alcohol, providing broad-spectrum antimicrobial activity against bacteria, fungi, and viruses, helping to prevent the spread of infections.
Uses & Indications
Dosage
Adults
For hygienic hand rub: Apply 3-5 mL to dry hands, rub thoroughly for 20-30 seconds until dry. For surgical hand scrub: Apply 5-10 mL, rub for 1-3 minutes (as per protocol) ensuring hands stay wet throughout, then rinse or rub until dry.
Elderly
Same as adults.
Renal_impairment
No adjustment needed (topical use).
How to Take
For external use only. Apply undiluted to dry hands. Ensure entire hand surface is covered, and rub vigorously until dry. Do not rinse with water.
Mechanism of Action
Chlorhexidine Gluconate exerts its antimicrobial effect by binding to the bacterial cell wall and disrupting its integrity, leading to leakage of intracellular components and cell death. Ethyl Alcohol denatures proteins and solubilizes lipids, rapidly inactivating microorganisms by disrupting their cell membranes and metabolic processes.
Pharmacokinetics
Onset
Seconds (due to alcohol)
Excretion
Not applicable (minimal systemic absorption)
Half life
Not applicable for topical antiseptic (local action)
Absorption
Minimal systemic absorption through intact skin. Primarily acts locally on the skin surface.
Metabolism
Not applicable (minimal systemic absorption)
Side Effects
Contraindications
- Hypersensitivity to Chlorhexidine Gluconate, Ethyl Alcohol, or any other component.
- Avoid use on open wounds, broken skin, or mucous membranes.
- Do not use in body cavities or as a pre-operative skin preparation for lumbar puncture or other meningeal procedures.
Drug Interactions
Other topical antiseptics/soaps
Avoid concurrent use with soaps or other anionic agents, as they may inactivate Chlorhexidine. Rinse thoroughly before using Hexisol-05-70-Hand-Rub if soap has been used.
Storage
Store below 30°C in a cool, dry place. Protect from light. Keep container tightly closed. Highly flammable, keep away from ignition sources.
Overdose
Accidental ingestion may cause gastric irritation, nausea, vomiting, or alcohol intoxication. If ingested, seek medical attention. Excessive topical use is unlikely to cause systemic toxicity but may lead to skin irritation.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation due to minimal systemic absorption. Consult a healthcare professional if concerns arise.
Side Effects
Contraindications
- Hypersensitivity to Chlorhexidine Gluconate, Ethyl Alcohol, or any other component.
- Avoid use on open wounds, broken skin, or mucous membranes.
- Do not use in body cavities or as a pre-operative skin preparation for lumbar puncture or other meningeal procedures.
Drug Interactions
Other topical antiseptics/soaps
Avoid concurrent use with soaps or other anionic agents, as they may inactivate Chlorhexidine. Rinse thoroughly before using Hexisol-05-70-Hand-Rub if soap has been used.
Storage
Store below 30°C in a cool, dry place. Protect from light. Keep container tightly closed. Highly flammable, keep away from ignition sources.
Overdose
Accidental ingestion may cause gastric irritation, nausea, vomiting, or alcohol intoxication. If ingested, seek medical attention. Excessive topical use is unlikely to cause systemic toxicity but may lead to skin irritation.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation due to minimal systemic absorption. Consult a healthcare professional if concerns arise.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date when stored correctly.
Availability
Pharmacies, supermarkets, healthcare facilities
Approval Status
Approved by regulatory bodies (e.g., DGDA, FDA, EMA)
Patent Status
Generic (Patent expired for main components)
WHO Essential Medicine
YesClinical Trials
Extensive clinical evidence supports the efficacy of alcohol and chlorhexidine in hand antisepsis; specific trials for this exact branded formulation may not be publicly available but ingredients are well-established.
Lab Monitoring
- Not required for routine topical use.
Doctor Notes
- Emphasize proper hand hygiene technique (WHO 6-step method).
- Advise patients on flammability and safe storage.
- Counsel on discontinuing use if persistent skin irritation occurs.
Patient Guidelines
- For external use only. Do not swallow.
- Avoid contact with eyes, ears, and mouth. If contact occurs, rinse thoroughly with water.
- Highly flammable. Keep away from heat, sparks, open flames, and hot surfaces.
- Keep out of reach of children.
- Discontinue use if irritation or rash develops.
Missed Dose Advice
Not applicable. Use as needed for hand hygiene.
Driving Precautions
No known effect on ability to drive or operate machinery.
Lifestyle Advice
- Practice good hand hygiene regularly.
- Use this product as part of a comprehensive hand hygiene routine.
- Store in a cool, dry place away from direct sunlight.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.