Hopso
Generic Name
Hopsonate 400 mg
Manufacturer
PharmaCorp Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| hopso 400 mg tablet | ৳ 450.00 | ৳ 3,150.00 |
Description
Overview of the medicine
Hopso 400 mg Tablet contains Hopsonate, a non-steroidal anti-inflammatory drug (NSAID) used for the relief of pain, inflammation, and fever associated with various conditions.
Uses & Indications
Dosage
Adults
Typically 400 mg every 4-6 hours as needed. Maximum daily dose 1200 mg.
Elderly
Lower doses may be required; caution advised due to potential renal impairment.
Renal_impairment
Dosage adjustment necessary; consult physician for specific recommendations.
How to Take
Take the tablet orally, preferably with food or milk to minimize gastrointestinal upset. Do not crush or chew.
Mechanism of Action
Hopsonate inhibits cyclooxygenase (COX-1 and COX-2) enzymes, thereby reducing the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever.
Pharmacokinetics
Onset
Within 30-60 minutes.
Excretion
Mainly excreted in urine as metabolites, with some fecal excretion.
Half life
Approximately 2-4 hours.
Absorption
Well absorbed orally; peak plasma concentrations reached within 1-2 hours.
Metabolism
Primarily metabolized in the liver via cytochrome P450 enzymes.
Side Effects
Contraindications
- Hypersensitivity to Hopsonate or other NSAIDs
- Active peptic ulcer or gastrointestinal bleeding
- Severe renal or hepatic impairment
- Severe heart failure
- Third trimester of pregnancy
Drug Interactions
Lithium
Increased plasma lithium levels.
Methotrexate
Increased methotrexate toxicity.
Diuretics and ACE inhibitors
Reduced efficacy and increased risk of renal impairment.
Anticoagulants (e.g., Warfarin)
Increased risk of bleeding.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include nausea, vomiting, epigastric pain, lethargy, and drowsiness. Management involves symptomatic and supportive care, gastric lavage, and activated charcoal.
Pregnancy & Lactation
Avoid use in the third trimester of pregnancy. Consult a doctor before use during the first two trimesters or while breastfeeding.
Side Effects
Contraindications
- Hypersensitivity to Hopsonate or other NSAIDs
- Active peptic ulcer or gastrointestinal bleeding
- Severe renal or hepatic impairment
- Severe heart failure
- Third trimester of pregnancy
Drug Interactions
Lithium
Increased plasma lithium levels.
Methotrexate
Increased methotrexate toxicity.
Diuretics and ACE inhibitors
Reduced efficacy and increased risk of renal impairment.
Anticoagulants (e.g., Warfarin)
Increased risk of bleeding.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include nausea, vomiting, epigastric pain, lethargy, and drowsiness. Management involves symptomatic and supportive care, gastric lavage, and activated charcoal.
Pregnancy & Lactation
Avoid use in the third trimester of pregnancy. Consult a doctor before use during the first two trimesters or while breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Generic available
Clinical Trials
Clinical trials have demonstrated the efficacy and safety of Hopsonate for pain and inflammation management. Further long-term studies are ongoing.
Lab Monitoring
- Complete blood count (CBC)
- Renal function tests (e.g., creatinine, BUN)
- Liver function tests (e.g., AST, ALT)
Doctor Notes
- Monitor patients for signs of GI bleeding and renal dysfunction, especially with prolonged use.
- Advise patients to report any unusual symptoms promptly.
- Consider proton pump inhibitors for high-risk patients on long-term therapy.
Patient Guidelines
- Always take with food or milk.
- Do not exceed the recommended dose.
- Report any signs of gastrointestinal bleeding immediately (e.g., black stools, vomiting blood).
- Avoid taking other NSAIDs concurrently without consulting your doctor.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness or drowsiness; if affected, avoid driving or operating machinery.
Lifestyle Advice
- Limit alcohol intake while on this medication.
- Stay hydrated by drinking plenty of fluids.
- Avoid prolonged sun exposure if photosensitivity occurs.
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Global Brand Names
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