Hunycof
Generic Name
Dextromethorphan Hydrobromide + Guaifenesin
Manufacturer
MediTop Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| hunycof 075 ml syrup | ৳ 50.00 | N/A |
Description
Overview of the medicine
Hunycof-075-ml-syrup is a cough syrup used to relieve cough associated with cold and flu, providing both cough suppression and expectorant action.
Uses & Indications
Dosage
Adults
Adults and Children 12 years and over: 10-20 ml every 4-6 hours as needed. Do not exceed 80 ml in 24 hours.
Elderly
Same as adult dose, consult physician for specific advice, especially if other medications are being taken.
Renal_impairment
Use with caution; dose adjustment may be necessary. Consult physician for specific guidance.
How to Take
Oral administration. Use the measuring cup or spoon provided for accurate dosing. Can be taken with or without food.
Mechanism of Action
Dextromethorphan suppresses the cough reflex by acting on the cough center in the medulla. Guaifenesin thins and loosens mucus, making it easier to cough up.
Pharmacokinetics
Onset
Dextromethorphan: 15-30 minutes; Guaifenesin: 30 minutes.
Excretion
Both Dextromethorphan and Guaifenesin are primarily excreted via the renal route (urine).
Half life
Dextromethorphan: 2-4 hours; Guaifenesin: 1 hour.
Absorption
Both Dextromethorphan and Guaifenesin are rapidly absorbed from the gastrointestinal tract.
Metabolism
Dextromethorphan: hepatic (primarily via CYP2D6). Guaifenesin: rapidly hydrolyzed in the liver.
Side Effects
Contraindications
- Hypersensitivity to Dextromethorphan, Guaifenesin, or any other component of the syrup.
- Concurrent use or within 14 days of discontinuing Monoamine Oxidase Inhibitors (MAOIs).
- Patients with chronic cough due to asthma, emphysema, or where cough is associated with excessive secretions.
Drug Interactions
MAOIs
Concurrent use may lead to serotonin syndrome, characterized by hyperthermia, rigidity, autonomic instability, and mental status changes. Avoid combination.
SSRIs and Tricyclic Antidepressants
Increased risk of serotonin syndrome due to additive serotonergic effects.
CNS Depressants (e.g., alcohol, sedatives, hypnotics)
May enhance the central nervous system depressant effects, leading to increased drowsiness or sedation.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Do not refrigerate. Keep the bottle tightly closed.
Overdose
Symptoms of overdose may include nausea, vomiting, dizziness, drowsiness, ataxia, nystagmus, respiratory depression, and hallucinations. In severe cases, coma and seizures may occur. Seek immediate medical attention. Management includes supportive care and activated charcoal.
Pregnancy & Lactation
Consult a doctor before use if pregnant or breastfeeding. Not recommended unless the potential benefits outweigh the potential risks to the fetus or infant.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture when stored as directed.
Availability
Pharmacies and Superstores
Approval Status
Approved by DGDA
Patent Status
Generic available
Clinical Trials
Specific clinical trials for the Hunycof brand are proprietary. However, the active ingredients Dextromethorphan and Guaifenesin have been extensively studied and are widely used in combination cough preparations.
Lab Monitoring
- No specific routine lab monitoring is generally required for short-term use of this medicine.
Doctor Notes
- Counsel patients on the proper dosage and the importance of not exceeding it.
- Advise patients about potential drowsiness and to avoid activities requiring mental alertness.
- Screen for concurrent use of MAOIs, SSRIs, or other CNS depressants.
Patient Guidelines
- Always read the label carefully before use.
- Do not exceed the recommended dose.
- Consult a doctor if cough persists for more than 7 days, recurs, or is accompanied by fever, rash, or persistent headache.
- Keep out of reach of children.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
This medicine may cause drowsiness or dizziness. Avoid driving or operating heavy machinery until you know how it affects you.
Lifestyle Advice
- Ensure adequate hydration by drinking plenty of fluids to help thin mucus.
- Avoid smoking and exposure to irritants that may worsen cough.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.