Hyginex
Generic Name
Ethanol (Alcohol) 96% Hand Rub
Manufacturer
XYZ Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
Variant | Unit Price | Strip Price |
---|---|---|
hyginex 96 3 hand rub | ৳ 100.00 | N/A |
Description
Overview of the medicine
Hyginex-96-3-Hand-Rub is an alcohol-based hand rub primarily used for rapid hand antisepsis to reduce the number of microorganisms on hands.
Uses & Indications
Dosage
Adults
For hygienic hand antisepsis: Apply 3-5 mL to dry hands, rub thoroughly for at least 20-30 seconds, ensuring all surfaces are covered, until dry. For surgical hand antisepsis: Apply a larger amount (e.g., 5-10 mL) and rub for 3-5 minutes, repeating as necessary.
Elderly
Same as adults.
Renal_impairment
Not applicable; primarily for external use.
How to Take
Ensure hands are visibly clean before applying. Dispense enough product to wet all surfaces of the hands, including between fingers and around nails. Rub hands together until the product is completely dry. Do not rinse with water or wipe with a towel.
Mechanism of Action
Ethanol denatures proteins and dissolves lipids, effectively disrupting cell membranes and inactivating enzymes of bacteria, viruses, and fungi, leading to their destruction.
Pharmacokinetics
Onset
Immediate (within seconds)
Excretion
Primarily evaporates from the skin surface. Any absorbed amount would be metabolized and excreted as with ingested ethanol.
Half life
Not applicable for topical hand rub; primarily evaporates.
Absorption
Minimal systemic absorption through intact skin. Significant absorption may occur through broken skin or with excessive use.
Metabolism
Not systemically metabolized via typical pathways in significant amounts with normal topical use.
Side Effects
Contraindications
- Hypersensitivity to ethanol or any other components of the formulation
- Application on broken skin, open wounds, or mucous membranes
- Use in infants without medical advice due to potential for alcohol absorption
Drug Interactions
Flammable materials
Keep away from heat, sparks, open flames, and hot surfaces. No smoking.
Other topical agents
Avoid simultaneous application with other topical agents to prevent potential inactivation or adverse skin reactions. Not known to have significant systemic drug interactions.
Storage
Store below 30°C in a cool, dry place. Keep away from direct sunlight, heat, and ignition sources. Ensure the container is tightly closed.
Overdose
Topical overdose is unlikely to cause systemic toxicity due to rapid evaporation. Accidental ingestion of large quantities can lead to alcohol poisoning, requiring immediate medical attention. Symptoms include nausea, vomiting, abdominal pain, dizziness, central nervous system depression, and in severe cases, respiratory depression and coma.
Pregnancy & Lactation
Generally considered safe for topical use during pregnancy and lactation as systemic absorption is minimal. However, caution is advised to avoid excessive use.
Side Effects
Contraindications
- Hypersensitivity to ethanol or any other components of the formulation
- Application on broken skin, open wounds, or mucous membranes
- Use in infants without medical advice due to potential for alcohol absorption
Drug Interactions
Flammable materials
Keep away from heat, sparks, open flames, and hot surfaces. No smoking.
Other topical agents
Avoid simultaneous application with other topical agents to prevent potential inactivation or adverse skin reactions. Not known to have significant systemic drug interactions.
Storage
Store below 30°C in a cool, dry place. Keep away from direct sunlight, heat, and ignition sources. Ensure the container is tightly closed.
Overdose
Topical overdose is unlikely to cause systemic toxicity due to rapid evaporation. Accidental ingestion of large quantities can lead to alcohol poisoning, requiring immediate medical attention. Symptoms include nausea, vomiting, abdominal pain, dizziness, central nervous system depression, and in severe cases, respiratory depression and coma.
Pregnancy & Lactation
Generally considered safe for topical use during pregnancy and lactation as systemic absorption is minimal. However, caution is advised to avoid excessive use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from the date of manufacture when stored properly.
Availability
Pharmacies, Supermarkets, General Stores
Approval Status
Approved for topical use
Patent Status
Not applicable for generic alcohol solutions
WHO Essential Medicine
YesClinical Trials
Extensive clinical evidence supports the efficacy of alcohol-based hand rubs for reducing healthcare-associated infections and promoting hand hygiene. Specific trials for Hyginex-96-3-Hand-Rub would focus on its formulation's specific antimicrobial efficacy and skin tolerance.
Lab Monitoring
- Not applicable for routine use of hand rub.
Doctor Notes
- Emphasize proper hand hygiene technique according to WHO guidelines.
- Advise patients on the importance of moisturizing hands to prevent dryness.
- Highlight flammability warnings and correct storage conditions.
Patient Guidelines
- For external use only. Do not ingest.
- Highly flammable: keep away from heat, open flames, and ignition sources.
- Avoid contact with eyes. If contact occurs, rinse thoroughly with water.
- Keep out of reach of children. Use in children should be supervised by an adult.
- Store in a cool, well-ventilated area.
Missed Dose Advice
Hyginex-96-3-Hand-Rub is used on an 'as needed' basis. If you miss a dose, simply use it when necessary. There is no scheduled dosing for this product.
Driving Precautions
No precautions needed as Hyginex-96-3-Hand-Rub is for external use and does not impair ability to drive or operate machinery.
Lifestyle Advice
- For visibly dirty hands, wash with soap and water before using hand rub.
- Moisturize hands regularly to prevent excessive dryness from frequent use.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.