Inosol
Generic Name
Myo-inositol
Manufacturer
Multiple manufacturers (e.g., Square Pharmaceuticals, Renata)
Country
Global, e.g., Bangladesh, India, USA
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Description
Overview of the medicine
Myo-inositol is a naturally occurring sugar alcohol found in various foods and the human body. It plays a crucial role in cell signaling and is often used as a dietary supplement, particularly for conditions like Polycystic Ovary Syndrome (PCOS), insulin resistance, and fertility issues. It is a precursor to inositol triphosphate, a secondary messenger system.
Uses & Indications
Dosage
Adults
Typically 2-4 grams daily, divided into two doses. For PCOS, 2 grams twice daily is common.
Elderly
No specific dosage adjustment usually required.
Renal_impairment
Use with caution in severe renal impairment, consultation with a doctor is advised.
How to Take
Mix powder sachets with water and drink. Capsules can be taken with or without food.
Mechanism of Action
Myo-inositol acts as a secondary messenger in various cellular processes, including insulin signaling. It is involved in glucose uptake and utilization, cell growth, and neurotransmitter regulation. In PCOS, it helps improve insulin sensitivity, reduce androgen levels, and restore ovulatory function.
Pharmacokinetics
Onset
Effects may take weeks to months to become noticeable.
Excretion
Primarily excreted in urine, some via feces.
Half life
Approximately 4-6 hours, but varies.
Absorption
Well absorbed from the gastrointestinal tract.
Metabolism
Metabolized to glucose or other inositol phosphates.
Side Effects
Contraindications
- Hypersensitivity to myo-inositol or any component of the formulation.
- Severe kidney disease (relative contraindication)
Drug Interactions
Lithium
Myo-inositol may reduce the effects of lithium, requiring dosage adjustments of lithium.
Antidiabetic drugs
May enhance the effects of antidiabetic drugs, potentially leading to hypoglycemia. Monitor blood glucose.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Generally well-tolerated, even at high doses. Symptoms of excessive intake may include mild gastrointestinal upset (nausea, gas, diarrhea). Management is supportive.
Pregnancy & Lactation
Generally considered safe during pregnancy and lactation, particularly for gestational diabetes. Consult a healthcare provider.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from manufacturing date.
Availability
Pharmacies, health stores, online
Approval Status
Marketed as dietary supplement; GRAS status in US
Patent Status
Generic, freely available
Clinical Trials
Numerous clinical trials support the efficacy of myo-inositol in improving outcomes for PCOS, insulin resistance, and fertility.
Lab Monitoring
- Blood glucose levels (for insulin resistance/diabetes)
- Hormone levels (for PCOS)
- Lipid profiles (for associated metabolic syndrome)
Doctor Notes
- Consider myo-inositol as an adjunct therapy for PCOS and insulin resistance.
- Advise patients on lifestyle modifications alongside supplementation.
- Regular follow-up is recommended to monitor efficacy and patient well-being.
Patient Guidelines
- Take as directed by your healthcare provider or package instructions.
- Consistency is key for observing benefits.
- Report any severe side effects to your doctor.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it's close to the next scheduled dose, skip the missed dose and resume your regular schedule. Do not double the dose.
Driving Precautions
No known impact on driving ability.
Lifestyle Advice
- Maintain a balanced diet.
- Engage in regular physical activity.
- Manage stress levels.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.