Iracet
Generic Name
Piracetam
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| iracet 250 mg tablet | ৳ 16.00 | ৳ 160.00 |
| iracet 500 mg tablet | ৳ 30.00 | ৳ 300.00 |
| iracet 500 mg injection | ৳ 40.13 | N/A |
| iracet 500 mg oral solution | ৳ 200.61 | N/A |
Description
Overview of the medicine
Iracet is used to improve cognitive functions such as memory, learning, and attention. It is also prescribed for cortical myoclonus.
Uses & Indications
Dosage
Adults
For cortical myoclonus: initially 7.2 g daily in 2-3 divided doses, increased by 4.8 g/day every 3-4 days up to a maximum of 24 g/day. For cognitive impairment: 2.4 g to 4.8 g daily in 2-3 divided doses.
Elderly
Similar to adults, but adjust dose based on renal function.
Renal_impairment
Dose reduction necessary based on creatinine clearance.
How to Take
Oral administration, with or without food. Tablets should be swallowed whole with water.
Mechanism of Action
Piracetam is believed to act on neuronal and vascular systems, improving the function of acetylcholine neurotransmission and enhancing cell membrane fluidity. It also enhances brain metabolism and protects against hypoxia.
Pharmacokinetics
Onset
Onset of action within 30-60 minutes.
Excretion
Primarily excreted unchanged via the kidneys.
Half life
Plasma half-life is approximately 4-5 hours; CSF half-life is 6-8 hours.
Absorption
Rapidly and almost completely absorbed after oral administration. Bioavailability is close to 100%.
Metabolism
Not metabolized in the human body.
Side Effects
Contraindications
- Hypersensitivity to piracetam or any excipients
- Severe renal impairment (creatinine clearance < 20 ml/min)
- Cerebral hemorrhage
- Huntington's chorea
Drug Interactions
Warfarin
Concomitant use with piracetam may prolong prothrombin time; close monitoring is recommended.
Thyroid hormones
Concomitant use may increase body weight, tremor, and confusion.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In cases of overdose, symptomatic and supportive measures should be taken. There is no specific antidote.
Pregnancy & Lactation
Not recommended during pregnancy and lactation unless clearly necessary, as piracetam crosses the placental barrier and is excreted in breast milk. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date
Availability
Pharmacies, hospitals
Approval Status
DGDA approved
Patent Status
Off-patent
Clinical Trials
Piracetam has been studied extensively, with varying results for different indications. It shows benefit in certain types of myoclonus and post-stroke cognitive deficits. Evidence for general cognitive enhancement in healthy individuals is mixed.
Lab Monitoring
- Renal function tests, especially in elderly patients or those with pre-existing renal impairment.
Doctor Notes
- Advise patients not to stop treatment abruptly.
- Monitor renal function, especially in elderly and patients with kidney impairment.
- Caution when co-administering with anticoagulants like warfarin.
Patient Guidelines
- Take the medicine regularly as prescribed by your doctor.
- Do not stop taking Iracet abruptly, as this may lead to withdrawal symptoms.
- Report any unusual side effects to your doctor.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Iracet may cause somnolence or dizziness in some patients. Patients should be advised to exercise caution when driving or operating machinery until they know how they react to the medicine.
Lifestyle Advice
- Maintain a healthy and balanced diet.
- Engage in regular physical activity.
- Avoid excessive alcohol consumption.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.