Isoben
Generic Name
Isoconazole Nitrate
Manufacturer
Global Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| isoben 25 01 lotion | ৳ 500.00 | N/A |
Description
Overview of the medicine
Isoben-25-01 Lotion is a topical antifungal medication used to treat various fungal infections of the skin.
Uses & Indications
Dosage
Adults
Apply thinly to the affected skin areas once daily. The duration of treatment depends on the extent and location of the infection, usually 2 to 4 weeks.
Elderly
No specific dosage adjustment is required for elderly patients. Use as per adult dosage.
Renal_impairment
No dosage adjustment needed due to minimal systemic absorption.
How to Take
For external use only. Clean and dry the affected area before applying a thin layer of lotion. Rub gently until it disappears. Wash hands after application.
Mechanism of Action
Isoconazole nitrate inhibits the biosynthesis of ergosterol, a vital component of the fungal cell membrane, leading to increased cell membrane permeability and eventual lysis of the fungal cell.
Pharmacokinetics
Onset
Symptomatic relief usually begins within a few days of treatment. Complete mycological cure may take longer, depending on the severity and type of infection.
Excretion
Excreted primarily via feces and, to a lesser extent, in urine after hepatic metabolism.
Half life
Systemic half-life is not clinically relevant for topical administration due to minimal absorption.
Absorption
Minimal systemic absorption occurs following topical application to intact or damaged skin. Less than 1% of the applied dose reaches systemic circulation.
Metabolism
Any absorbed portion is metabolized in the liver to inactive metabolites.
Side Effects
Contraindications
- Known hypersensitivity to isoconazole nitrate or any other imidazole derivative.
- Hypersensitivity to any excipients in the formulation.
Drug Interactions
Systemic drugs
Due to minimal systemic absorption, clinically significant drug interactions are unlikely with topical isoconazole nitrate.
Storage
Store below 30°C in a cool, dry place. Protect from direct sunlight and moisture. Keep out of reach of children.
Overdose
Overdose with topical application is highly unlikely due to minimal systemic absorption. In case of accidental ingestion, supportive and symptomatic treatment should be given.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy and lactation should only be considered if the potential benefit outweighs the potential risk to the fetus or infant. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24 to 36 months from the date of manufacture. Check the packaging for the exact expiry date.
Availability
Pharmacies
Approval Status
Approved
Patent Status
Generic
Clinical Trials
Clinical trials have demonstrated the efficacy and safety of isoconazole nitrate in the treatment of various superficial fungal infections, showing comparable outcomes to other topical antifungals.
Lab Monitoring
- Routine laboratory monitoring is not typically required for topical isoconazole nitrate.
Doctor Notes
- Advise patients to complete the full course of treatment to prevent recurrence.
- Educate patients on proper hygiene practices to minimize reinfection risk.
- Monitor for signs of hypersensitivity reactions; discontinue if observed.
Patient Guidelines
- Use the lotion for the full prescribed duration, even if symptoms improve.
- Avoid contact with eyes, mouth, and other mucous membranes.
- If irritation occurs, discontinue use and consult your doctor.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.
Driving Precautions
Isoben-25-01 Lotion does not affect the ability to drive or operate machinery.
Lifestyle Advice
- Keep the affected area clean and dry.
- Wear loose, breathable clothing.
- Avoid sharing towels, clothing, and personal items to prevent spreading infection.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.