Itchin-DS
Generic Name
Olopatadine Hydrochloride
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| itchin ds 4 eye drop | ৳ 75.23 | N/A |
Description
Overview of the medicine
Itchin-DS 4 Eye Drop contains Olopatadine, an ophthalmic antihistamine and mast cell stabilizer, used to relieve ocular itching associated with allergic conjunctivitis.
Uses & Indications
Dosage
Adults
Instill one drop in the affected eye(s) twice daily, approximately 6 to 8 hours apart.
Elderly
No dosage adjustment is typically required.
Renal_impairment
No dosage adjustment is typically required.
How to Take
For ophthalmic use only. Tilt head back, pull down the lower eyelid, and instill one drop into the conjunctival sac. Avoid touching the dropper tip to the eye or any other surface to prevent contamination.
Mechanism of Action
Olopatadine acts as a selective H1-receptor antagonist and mast cell stabilizer. It inhibits the release of histamine from mast cells and antagonizes H1 receptors on conjunctival epithelial cells, thereby preventing and relieving ocular allergic symptoms.
Pharmacokinetics
Onset
Within minutes of instillation.
Excretion
Mainly via renal excretion, with approximately 60-70% excreted unchanged in urine.
Half life
Approximately 3 hours systemically, though local effects can last longer.
Absorption
Minimal systemic absorption after ocular administration. Peak plasma concentrations are typically reached within 2 hours.
Metabolism
Primarily metabolized in the liver to two minor metabolites.
Side Effects
Contraindications
- Known hypersensitivity to olopatadine hydrochloride or any component of the formulation
Drug Interactions
None clinically significant for ophthalmic use
Due to minimal systemic absorption, systemic drug interactions are unlikely with ophthalmic olopatadine.
Storage
Store at room temperature (15-30°C). Protect from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Accidental ingestion of a bottle's contents is unlikely to cause serious problems. Symptoms of oral overdose may include drowsiness. Management is supportive and symptomatic.
Pregnancy & Lactation
Use during pregnancy only if clearly needed and the potential benefits justify the potential risks to the fetus. Exercise caution when administered to a nursing woman as it is unknown if olopatadine is excreted in human milk.
Side Effects
Contraindications
- Known hypersensitivity to olopatadine hydrochloride or any component of the formulation
Drug Interactions
None clinically significant for ophthalmic use
Due to minimal systemic absorption, systemic drug interactions are unlikely with ophthalmic olopatadine.
Storage
Store at room temperature (15-30°C). Protect from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Accidental ingestion of a bottle's contents is unlikely to cause serious problems. Symptoms of oral overdose may include drowsiness. Management is supportive and symptomatic.
Pregnancy & Lactation
Use during pregnancy only if clearly needed and the potential benefits justify the potential risks to the fetus. Exercise caution when administered to a nursing woman as it is unknown if olopatadine is excreted in human milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months (unopened); discard 28 days after opening the container.
Availability
Pharmacies
Approval Status
Approved
Patent Status
Generic available
Clinical Trials
Clinical trials have demonstrated the efficacy and safety of olopatadine 0.4% in treating ocular itching associated with allergic conjunctivitis, showing rapid onset of action and sustained relief.
Lab Monitoring
- Not typically required for routine ophthalmic use of olopatadine.
Doctor Notes
- Emphasize proper instillation technique to patients.
- Advise patients not to share eye drops to prevent cross-contamination.
- Monitor for resolution of symptoms and any signs of adverse reactions.
Patient Guidelines
- Do not wear contact lenses if your eyes are red.
- Wait at least 10 minutes after instilling the eye drop before inserting contact lenses (if approved for use).
- Avoid touching the dropper tip to prevent contamination.
- Consult your doctor if symptoms worsen or do not improve.
Missed Dose Advice
If a dose is missed, apply it as soon as remembered. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose.
Driving Precautions
Itchin-DS 4 Eye Drop may cause temporary blurred vision. Patients should be advised not to drive or operate machinery until their vision is clear.
Lifestyle Advice
- Avoid known allergens that trigger allergic conjunctivitis symptoms (e.g., pollen, pet dander).
- Maintain good hand hygiene before and after applying eye drops.
- Avoid rubbing your eyes, as this can worsen irritation.
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Global Brand Names
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