K-Nor
Generic Name
Azithromycin Suspension
Manufacturer
Medipharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| k nor 99934 w suspension | ৳ 980.00 | N/A |
Description
Overview of the medicine
K-Nor 200 mg/5 mL Suspension is a macrolide antibiotic used to treat various bacterial infections, including respiratory tract infections, skin infections, and certain sexually transmitted diseases. It works by stopping the growth of bacteria.
Uses & Indications
Dosage
Adults
For specific adult indications requiring suspension, consult physician. Typical adult dose for tablets is 500 mg once daily for 3 days or 500 mg on day 1 followed by 250 mg for 4 days.
Elderly
No specific dosage adjustment required, but monitor for side effects.
Renal_impairment
No dosage adjustment needed for mild to moderate impairment. Use with caution in severe renal impairment.
How to Take
Shake well before use. Administer orally once daily, with or without food. Use an accurate measuring device (e.g., oral syringe or measuring spoon provided).
Mechanism of Action
Azithromycin works by binding to the 50S ribosomal subunit of susceptible bacteria, thereby inhibiting protein synthesis. This bacteriostatic action prevents bacterial growth and replication.
Pharmacokinetics
Onset
Clinical effects typically within 2-3 days.
Excretion
Primarily excreted unchanged in bile; minor renal excretion.
Half life
Terminal half-life is 2-4 days.
Absorption
Rapidly absorbed from the GI tract, bioavailability is approximately 37%.
Metabolism
Undergoes hepatic metabolism, primarily N-demethylation.
Side Effects
Contraindications
- •Hypersensitivity to azithromycin, erythromycin, or any macrolide or ketolide antibiotic
- •History of cholestatic jaundice/hepatic dysfunction associated with prior azithromycin use
Drug Interactions
Antacids
Concurrent use may decrease peak serum concentrations of azithromycin. Administer azithromycin at least 1 hour before or 2 hours after antacids.
Warfarin
Increased anticoagulant effect may occur. Monitor INR closely.
Nelfinavir
Increased azithromycin concentrations. No dose adjustment needed but monitor for side effects.
Storage
Store dry powder below 30°C, protected from light and moisture. Store reconstituted suspension below 30°C, do not refrigerate.
Overdose
Symptoms of overdose include severe nausea, vomiting, diarrhea, and reversible hearing loss. Gastric lavage and general supportive measures are indicated.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Azithromycin is excreted in breast milk; caution advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months for dry powder. Reconstituted suspension is stable for 10 days at room temperature (below 30°C).
Availability
Available in pharmacies and hospitals
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Patent Expired
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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