Take Karvela 800 mg Tablet orally, preferably with food or milk to reduce stomach upset. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break it.

Ibuprofen works by inhibiting the synthesis of prostaglandins, which are chemicals in the body that contribute to pain, inflammation, and fever. It achieves this by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes.

• •Hypersensitivity to Ibuprofen or other NSAIDs.
• •History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.
• •Active or history of recurrent peptic ulcer/hemorrhage.
• •Severe heart failure, renal failure, or hepatic failure.
• •Third trimester of pregnancy.

Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.

Symptoms of overdose include nausea, vomiting, abdominal pain, drowsiness, dizziness, tinnitus, and sometimes convulsions. Severe overdose may lead to acute renal failure, hepatic damage, and respiratory depression. Management involves symptomatic and supportive care, gastric lavage, activated charcoal, and monitoring of vital signs.

Not recommended during the third trimester of pregnancy due to potential fetal harm and interference with labor. Use with caution during the first and second trimesters and during lactation, only if the potential benefit outweighs the risk.