Larocent
Generic Name
Laromycin
Manufacturer
Acme Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| larocent 100 mg capsule | ৳ 900.00 | ৳ 5,400.00 |
Description
Overview of the medicine
Larocent 100 mg Capsule contains Laromycin, an antibiotic used to treat various bacterial infections.
Uses & Indications
Dosage
Adults
100 mg twice daily (every 12 hours) for 7-14 days, depending on the severity and type of infection. Max dose 200 mg/day.
Elderly
No specific dose adjustment generally required based on age alone, but monitor renal and hepatic function.
Renal_impairment
Dose reduction may be necessary in severe renal impairment (e.g., Creatinine Clearance < 30 mL/min). Consult a physician.
How to Take
Take orally with a glass of water, with or without food. Complete the full course as prescribed.
Mechanism of Action
Laromycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby stopping bacterial growth.
Pharmacokinetics
Onset
Therapeutic effects typically observed within 1-2 hours after administration.
Excretion
Mainly excreted via bile (60%) and urine (40%) as unchanged drug and metabolites.
Half life
Elimination half-life averages 6-8 hours, allowing for twice-daily dosing.
Absorption
Rapidly absorbed from the gastrointestinal tract, bioavailability of about 80%.
Metabolism
Primarily metabolized in the liver via cytochrome P450 enzymes.
Side Effects
Contraindications
- •Hypersensitivity to Laromycin or any macrolide antibiotics
- •Severe hepatic dysfunction
- •Concurrent use with drugs known to prolong the QT interval
Drug Interactions
Digoxin
May increase serum digoxin levels; monitor digoxin concentrations.
Warfarin
May enhance the anticoagulant effect, requiring close monitoring of INR.
Statins (e.g., Simvastatin)
Increased risk of myopathy and rhabdomyolysis.
Antacids (containing aluminum or magnesium)
May reduce the absorption of Laromycin; separate administration by at least 2 hours.
Storage
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, seek immediate medical attention. Management includes symptomatic and supportive treatment; gastric lavage may be considered within the first hour of ingestion.
Pregnancy & Lactation
Use in pregnancy only if clearly needed and the potential benefits outweigh the potential risks to the fetus. Laromycin is excreted in breast milk; use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from the date of manufacture.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Patent expired
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Global Brand Names
International brand names for this medicine
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