Lasocon
Generic Name
Lansoprazole 30 mg
Manufacturer
General Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| lasocon 30 mg capsule | ৳ 6.00 | ৳ 24.00 |
Description
Overview of the medicine
Lansoprazole is a proton pump inhibitor used to treat stomach and esophageal problems like acid reflux (GERD) and ulcers. It works by decreasing the amount of acid your stomach makes.
Uses & Indications
Dosage
Adults
Duodenal ulcer: 30 mg once daily for 4 weeks. Gastric ulcer: 30 mg once daily for 8 weeks. Reflux esophagitis: 30 mg once daily for 4-8 weeks.
Elderly
No dosage adjustment generally required, but caution is advised in patients with severe hepatic impairment.
Renal_impairment
No dosage adjustment required.
How to Take
Take capsule whole, do not crush or chew. Should be taken before meals, preferably in the morning.
Mechanism of Action
Lansoprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase enzyme system at the secretory surface of the gastric parietal cell.
Pharmacokinetics
Onset
Within 1-2 hours.
Excretion
Primarily excreted in urine (approximately 33%) and feces (approximately 67%).
Half life
1.3 to 1.7 hours.
Absorption
Rapidly absorbed after oral administration. Bioavailability is about 80-90%.
Metabolism
Extensively metabolized in the liver, primarily by CYP2C19 and CYP3A4.
Side Effects
Contraindications
- Hypersensitivity to lansoprazole or any component of the formulation
- Concomitant use with atazanavir
Drug Interactions
Warfarin
Increased INR/bleeding risk
Sucralfate/Antacids
Reduced bioavailability of lansoprazole; take lansoprazole 30 minutes before antacids/sucralfate
Ketoconazole, Itraconazole
Decreased absorption due to altered gastric pH
Storage
Store in a cool, dry place, away from light. Do not store above 30°C.
Overdose
No specific antidote. Symptomatic and supportive treatment. Lansoprazole is not significantly removed by hemodialysis.
Pregnancy & Lactation
Pregnancy Category B. Use during pregnancy only if clearly needed. Exercise caution in breastfeeding as it is excreted in breast milk.
Side Effects
Contraindications
- Hypersensitivity to lansoprazole or any component of the formulation
- Concomitant use with atazanavir
Drug Interactions
Warfarin
Increased INR/bleeding risk
Sucralfate/Antacids
Reduced bioavailability of lansoprazole; take lansoprazole 30 minutes before antacids/sucralfate
Ketoconazole, Itraconazole
Decreased absorption due to altered gastric pH
Storage
Store in a cool, dry place, away from light. Do not store above 30°C.
Overdose
No specific antidote. Symptomatic and supportive treatment. Lansoprazole is not significantly removed by hemodialysis.
Pregnancy & Lactation
Pregnancy Category B. Use during pregnancy only if clearly needed. Exercise caution in breastfeeding as it is excreted in breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Lansoprazole has been extensively studied in various clinical trials demonstrating its efficacy and safety for the treatment of acid-related disorders.
Lab Monitoring
- Liver function tests (in patients with severe hepatic impairment)
- Serum magnesium levels (with prolonged use, >1 year)
Doctor Notes
- Consider bone density monitoring for patients on long-term PPI therapy.
- Advise patients on lifestyle modifications to manage GERD symptoms.
- Review need for continued PPI therapy periodically.
Patient Guidelines
- Do not stop taking the medicine suddenly without consulting your doctor.
- Inform your doctor about all other medications you are taking.
- Report any severe or persistent side effects.
Missed Dose Advice
Take the missed dose as soon as you remember, unless it is almost time for your next dose. Do not take a double dose.
Driving Precautions
May cause dizziness or visual disturbances; caution advised when driving or operating machinery.
Lifestyle Advice
- Avoid spicy and fatty foods.
- Limit alcohol and caffeine intake.
- Maintain a healthy weight and avoid smoking.
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.