Levotiz
Generic Name
Levocetirizine
Manufacturer
Acme Laboratories Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| levotiz 5 mg tablet | ৳ 2.50 | ৳ 25.00 |
Description
Overview of the medicine
Levotiz 5 mg Tablet contains Levocetirizine, a potent antihistamine used to relieve symptoms associated with allergic conditions such as hay fever, chronic urticaria, and allergic rhinitis.
Uses & Indications
Dosage
Adults
Adults and adolescents 12 years and older: 5 mg once daily in the evening.
Elderly
Dosage adjustment may be necessary in elderly patients with impaired renal function.
Renal_impairment
Mild renal impairment: 2.5 mg once daily. Moderate renal impairment: 2.5 mg every other day. Severe renal impairment: Contraindicated.
How to Take
Levotiz 5 mg Tablet should be taken orally with or without food, preferably in the evening. Swallow the tablet whole with water.
Mechanism of Action
Levocetirizine is a potent, selective, peripheral H1-receptor antagonist. It blocks the action of histamine, a natural substance in the body that causes allergic symptoms, thereby alleviating itching, sneezing, watery eyes, and runny nose.
Pharmacokinetics
Onset
Within 15-30 minutes
Excretion
Primarily excreted unchanged in the urine (about 85%) and feces (about 13%).
Half life
Approximately 7-10 hours
Absorption
Rapidly and extensively absorbed from the gastrointestinal tract after oral administration.
Metabolism
Minimally metabolized in the liver (less than 14% of the dose).
Side Effects
Contraindications
- •Hypersensitivity to levocetirizine, cetirizine, or any piperazine derivative
- •Patients with severe renal impairment (creatinine clearance less than 10 mL/min)
- •Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption
Drug Interactions
Alcohol
Concurrent use with alcohol may further decrease alertness and impair central nervous system performance.
Ritonavir
May increase plasma concentration of levocetirizine.
CNS Depressants
Concurrent use with other CNS depressants (e.g., sedatives, tranquilizers) may increase the risk of CNS depression.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include drowsiness in adults and agitation or restlessness followed by drowsiness in children. Treatment is symptomatic and supportive. Gastric lavage and activated charcoal may be considered shortly after ingestion.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Excreted in breast milk, so caution is advised during breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from manufacturing date.
Availability
Pharmacies, hospitals, clinics
Approval Status
Approved by regulatory bodies (e.g., FDA, DGDA)
Patent Status
Off-patent
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Global Brand Names
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