Lorix
Generic Name
lorix-5-w-cream
Manufacturer
Medix Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| lorix 5 w cream | ৳ 60.00 | N/A |
Description
Overview of the medicine
Lorix-5-W-Cream is a topical preparation containing a synthetic anti-inflammatory agent and a broad-spectrum antimicrobial agent. It is used to treat various skin conditions where both inflammation and bacterial infection are present or suspected. The cream helps to reduce redness, swelling, and itching while fighting off susceptible bacteria.
Uses & Indications
Dosage
Adults
Apply a thin layer to the affected skin area 2 to 3 times daily, or as directed by a physician. Gently rub in. Do not use for more than 7 days without medical review.
Elderly
No specific dosage adjustment required; use with caution for prolonged periods due to thinning skin.
Renal_impairment
No specific dosage adjustment required for topical use.
How to Take
For external topical use only. Wash and dry the affected area before application. Apply a thin layer of cream and gently rub it into the skin. Wash hands after application unless hands are the treated area. Avoid contact with eyes, nose, mouth, and other mucous membranes.
Mechanism of Action
The anti-inflammatory component works by inhibiting the release of inflammatory mediators (e.g., prostaglandins, leukotrienes), thereby reducing swelling, redness, and itching. The antimicrobial component acts by interfering with bacterial cell wall synthesis or protein synthesis, leading to bacterial death and preventing the spread of infection.
Pharmacokinetics
Onset
Anti-inflammatory effects typically begin within a few hours; antimicrobial effects may take 2-3 days to be noticeable.
Excretion
Metabolites are excreted mainly via urine and feces.
Half life
Not precisely determined for topical application due to minimal systemic absorption; local effects persist for several hours.
Absorption
Minimal systemic absorption occurs after topical application, primarily confined to the skin layers. Absorption may increase with prolonged use, application to large surface areas, or occlusive dressings.
Metabolism
Any absorbed portion is primarily metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to any component of Lorix-5-W-Cream
- Tuberculosis of the skin, viral skin infections (e.g., herpes simplex, varicella), fungal skin infections (unless specifically indicated)
- Perioral dermatitis, rosacea, acne vulgaris
Drug Interactions
No significant systemic drug interactions are expected with topical use.
However, prolonged use on large areas might lead to minimal systemic absorption, potentially interacting with systemic corticosteroids or other immunosuppressants.
Storage
Store below 30°C in a dry place, away from light. Do not freeze. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause acute systemic effects. Chronic overdose or misuse (e.g., using large amounts over large areas for prolonged periods) may lead to systemic effects such as adrenal suppression. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Use during pregnancy and lactation should only be considered if the potential benefit outweighs the potential risk to the fetus or infant. Consult a physician before use. Avoid applying to large areas or for prolonged periods.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Available in pharmacies and hospitals nationwide
Approval Status
Approved by DGDA, Bangladesh
Patent Status
Generic versions available
Clinical Trials
Specific clinical trial data for 'Lorix-5-W-Cream' as a generic name may not be publicly available. However, active ingredients within similar combination creams have undergone extensive clinical trials.
Lab Monitoring
- Routine lab monitoring is not typically required for topical use. For extensive or prolonged use, monitoring of adrenal function (e.g., plasma cortisol levels) may be considered.
Doctor Notes
- Emphasize short-term use, especially on sensitive areas like the face or in children.
- Advise patients on proper application technique and warning signs for adverse reactions.
- Consider fungal or viral etiology if the condition worsens or fails to respond, as this cream is primarily antibacterial and anti-inflammatory.
Patient Guidelines
- Use only as directed by your doctor. Do not exceed the prescribed duration of treatment.
- Avoid applying the cream to open wounds, mucous membranes, or near the eyes.
- Inform your doctor if your condition worsens or shows no improvement after a few days of use.
Missed Dose Advice
If a dose is missed, apply it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.
Driving Precautions
Lorix-5-W-Cream is for topical use and is not expected to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain good skin hygiene to prevent further infections.
- Avoid scratching affected areas to prevent worsening of symptoms and secondary infections.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.