Lurex
Generic Name
Ambroxol Hydrochloride
Manufacturer
Hypothetical Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| lurex 30 mg syrup | ৳ 55.00 | N/A |
Description
Overview of the medicine
Lurex 30 mg Syrup contains Ambroxol Hydrochloride, a mucolytic agent used to thin and loosen mucus in the airways, making it easier to cough up. It is commonly used in respiratory conditions such as acute and chronic bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport.
Uses & Indications
Dosage
Adults
Adults and children over 12 years: 10 ml (60 mg) twice daily or 5 ml (30 mg) three times daily.
Elderly
No specific dosage adjustment required, but caution in patients with severe hepatic or renal impairment.
Renal_impairment
A reduction in dose or an increase in the interval between doses may be necessary in severe renal impairment.
How to Take
Oral administration. May be taken with or without food. Use a measuring spoon or cup for accurate dosage.
Mechanism of Action
Ambroxol acts as a mucolytic by depolymerizing mucopolysaccharide fibers and stimulating the production of less viscous mucus, thereby facilitating mucociliary clearance. It also exhibits anti-inflammatory and antioxidant properties.
Pharmacokinetics
Onset
Within 30 minutes to 2 hours.
Excretion
Primarily renally (approx. 90% as metabolites).
Half life
Approximately 7-12 hours.
Absorption
Rapid and almost complete absorption after oral administration.
Metabolism
Extensive first-pass metabolism in the liver to various metabolites.
Side Effects
Contraindications
- Hypersensitivity to Ambroxol or any component of the formulation.
- Hereditary fructose intolerance (due to sorbitol in some formulations).
Drug Interactions
Antitussives (e.g., dextromethorphan)
Concomitant use with antitussives may lead to a dangerous accumulation of bronchial secretions due to inhibition of the cough reflex.
Antibiotics (e.g., amoxicillin, cefuroxime, erythromycin, doxycycline)
Ambroxol can increase the penetration of some antibiotics into bronchial secretions, potentially enhancing their effect.
Storage
Store below 30°C, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose are generally mild and may include gastrointestinal disturbances. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Pregnancy Category C. Use with caution during pregnancy, especially during the first trimester, only if clearly needed. Excreted into breast milk; caution advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Pharmacies, drugstores
Approval Status
Approved by regulatory bodies in most countries
Patent Status
Off-patent
Clinical Trials
Extensively studied in clinical trials for its mucolytic and expectorant properties across various respiratory conditions. Studies have shown efficacy in improving sputum viscosity and mucociliary clearance.
Lab Monitoring
- No specific routine lab monitoring required.
Doctor Notes
- Advise patients to increase fluid intake.
- Monitor for signs of allergic reactions, especially skin rashes.
- Caution in patients with a history of gastric ulcer due to potential for gastric irritation.
Patient Guidelines
- Drink plenty of fluids to help loosen mucus.
- Do not use for persistent or chronic cough without consulting a doctor.
- Report any skin rash immediately to your doctor.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Ambroxol is generally not expected to affect the ability to drive or operate machinery. However, individual responses may vary.
Lifestyle Advice
- Maintain good hydration.
- Avoid smoking and exposure to irritants that may worsen respiratory conditions.
- Practice good cough etiquette.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.