M-beg
Generic Name
Mebeverine Hydrochloride
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| m beg 25 mg tablet | ৳ 30.00 | ৳ 300.00 |
| m beg 50 mg tablet | ৳ 55.00 | ৳ 550.00 |
Description
Overview of the medicine
M-beg (Mebeverine Hydrochloride) is an antispasmodic medicine used to relieve symptoms of irritable bowel syndrome (IBS) and other related conditions, such as abdominal pain and cramps, persistent diarrhoea, and flatulence. It works by relaxing the smooth muscles of the gut.
Uses & Indications
Dosage
Adults
One 135 mg tablet three times a day, preferably 20 minutes before meals.
Elderly
No specific dosage adjustment is required, but caution is advised in frail elderly patients.
Renal_impairment
No specific dosage adjustment is required for mild to moderate renal impairment. Use with caution in severe impairment.
How to Take
Oral. Tablets should be swallowed whole with water, preferably 20 minutes before meals. Do not chew or crush.
Mechanism of Action
Mebeverine acts directly on the smooth muscle of the gastrointestinal tract, relieving spasm without affecting normal gut motility. It is believed to work by blocking calcium channels in the smooth muscle cells.
Pharmacokinetics
Onset
Within 1 hour
Excretion
Mainly excreted in the urine as metabolites.
Half life
Short (approximately 1-2.5 hours for metabolites)
Absorption
Rapidly and completely absorbed after oral administration.
Metabolism
Extensively metabolized by esterases into mebeverinic acid and an alcohol metabolite, which are further metabolized.
Side Effects
Contraindications
- Hypersensitivity to mebeverine or any excipients
- Paralytic ileus
Drug Interactions
None
No clinically significant drug interactions have been reported with mebeverine.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
In case of overdose, symptoms may include central nervous system excitability. Treatment is symptomatic and supportive; no specific antidote is known.
Pregnancy & Lactation
Use during pregnancy and lactation should only be considered if the potential benefits outweigh the potential risks. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies, hospitals
Approval Status
Approved by health authorities
Patent Status
Patent expired
Clinical Trials
Mebeverine has been studied in numerous clinical trials for its efficacy and safety in IBS management. Studies confirm its role as an effective antispasmodic.
Lab Monitoring
- No specific lab monitoring is generally required for mebeverine.
Doctor Notes
- Consider lifestyle modifications alongside medication for IBS.
- Educate patients on proper administration and potential side effects.
- Re-evaluate diagnosis if symptoms do not improve.
Patient Guidelines
- Take as directed by your doctor.
- Do not exceed the recommended dose.
- If symptoms persist, consult your doctor.
Missed Dose Advice
If a dose is missed, skip the missed dose and continue with the regular schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Mebeverine is not known to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a healthy diet rich in fiber.
- Stay hydrated.
- Manage stress, as it can worsen IBS symptoms.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.