Magasol
Generic Name
Magaldrate
Manufacturer
Reputable Pharmaceutical Company
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| magasol 480 mg suspension | ৳ 110.00 | N/A |
Description
Overview of the medicine
Magasol 480 mg Suspension is an antacid medication used to relieve symptoms of heartburn, indigestion, and acid reflux. It contains Magaldrate, which neutralizes excess stomach acid.
Uses & Indications
Dosage
Adults
10 ml (480 mg) four times daily, between meals and at bedtime, or as directed by physician.
Elderly
No specific dose adjustment is generally required, but caution is advised in patients with renal impairment.
Renal_impairment
Use with caution. Reduced doses or avoidance may be necessary due to potential for aluminum and magnesium accumulation.
How to Take
Shake the bottle well before each use. Take orally, usually between meals and at bedtime. Do not exceed the recommended dose.
Mechanism of Action
Magaldrate is a hybrid antacid that combines aluminum and magnesium hydroxides in a unique chemical structure. It neutralizes gastric acid by forming a protective layer over the esophageal and gastric mucosa, leading to a rapid and sustained reduction in gastric acidity.
Pharmacokinetics
Onset
Within 5-10 minutes
Excretion
Aluminum and magnesium salts are primarily excreted in feces. Small absorbed amounts are excreted renally.
Half life
Not directly applicable for antacids with local action; components are excreted.
Absorption
Minimal systemic absorption of aluminum and magnesium ions. Primarily acts locally in the gastrointestinal tract.
Metabolism
Not significantly metabolized systemically.
Side Effects
Contraindications
- •Hypersensitivity to Magaldrate or any components of the suspension
- •Severe renal impairment
Drug Interactions
Iron supplements
May reduce absorption of iron. Separate administration times.
Digoxin, Phenytoin
May reduce absorption.
Tetracyclines & Fluoroquinolones
May decrease absorption of these antibiotics. Administer Magasol at least 2 hours before or after.
Storage
Store below 30°C in a cool, dry place, away from light. Do not freeze. Keep out of reach of children.
Overdose
Overdose is rare due to low systemic absorption. Symptoms may include diarrhea, abdominal pain, and constipation. In patients with severe renal impairment, accumulation of aluminum and magnesium may lead to hypermagnesemia or aluminum toxicity. Treatment is supportive.
Pregnancy & Lactation
Use with caution. Consult a doctor before use during pregnancy and lactation. Minimal systemic absorption suggests low risk, but specific studies are limited.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date
Availability
Pharmacies, drugstores
Approval Status
Approved by DGDA
Patent Status
Generic; patent expired
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Global Brand Names
International brand names for this medicine
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