Mavixen
Generic Name
Mavixen 100 mg tablet
Manufacturer
MediCorp Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| mavixen 100 mg tablet | ৳ 4,000.00 | N/A |
Description
Overview of the medicine
Mavixen 100 mg tablet is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and lower fever. It works by blocking certain natural substances in the body that cause inflammation.
Uses & Indications
Dosage
Adults
100 mg orally, 2-3 times daily, or as directed by a physician. Max dose: 300 mg/day.
Elderly
Lower doses may be required, closely monitor for adverse effects.
Renal_impairment
Use with caution; dose adjustment may be necessary based on creatinine clearance.
How to Take
Take the tablet whole with a glass of water, preferably with or after food to minimize gastrointestinal upset. Do not chew or crush.
Mechanism of Action
Mavixen inhibits cyclooxygenase (COX-1 and COX-2) enzymes, which are responsible for the synthesis of prostaglandins. Prostaglandins are mediators of inflammation, pain, and fever. By reducing prostaglandin production, Mavixen alleviates these symptoms.
Pharmacokinetics
Onset
Within 30-60 minutes.
Excretion
Excreted mainly via urine (metabolites) and a small amount in feces.
Half life
Approximately 2-4 hours.
Absorption
Rapidly and almost completely absorbed from the gastrointestinal tract after oral administration.
Metabolism
Primarily metabolized in the liver via cytochrome P450 enzymes.
Side Effects
Contraindications
- •Known hypersensitivity to Mavixen or other NSAIDs (e.g., aspirin)
- •Active gastrointestinal bleeding or peptic ulcer
- •Severe renal or hepatic impairment
- •Severe heart failure
- •Third trimester of pregnancy
Drug Interactions
Lithium
Increased plasma lithium levels, potentially leading to toxicity.
Methotrexate
Increased methotrexate toxicity.
Corticosteroids
Increased risk of gastrointestinal ulceration and bleeding.
ACE Inhibitors/ARBs
Reduced antihypertensive effect and increased risk of renal impairment.
Diuretics (e.g., Furosemide)
Reduced diuretic effect and increased risk of renal impairment.
Anticoagulants (e.g., Warfarin)
Increased risk of bleeding.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include nausea, vomiting, epigastric pain, lethargy, drowsiness. In severe cases, gastrointestinal bleeding, acute renal failure, coma, and convulsions may occur. Treatment is symptomatic and supportive; gastric lavage or activated charcoal may be considered soon after ingestion.
Pregnancy & Lactation
Avoid during the third trimester of pregnancy due to potential fetal harm (premature closure of the ductus arteriosus). Use with caution in earlier trimesters and during lactation; consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from the date of manufacture
Availability
Available in pharmacies nationwide
Approval Status
Approved by regulatory authorities
Patent Status
Patented by the manufacturer
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Global Brand Names
International brand names for this medicine
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