Maxpain
Generic Name
Ibuprofen
Manufacturer
Generic Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
Variant | Unit Price | Strip Price |
---|---|---|
maxpain 100 mg tablet | ৳ 3.50 | N/A |
Description
Overview of the medicine
Maxpain 100 mg tablet contains Ibuprofen, a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and lower fever. It is commonly used for headaches, menstrual cramps, dental pain, muscle aches, and arthritis.
Uses & Indications
Dosage
Adults
Oral: 200-400 mg every 4-6 hours as needed, not exceeding 1200 mg in 24 hours without medical supervision. For 100 mg, typically 2 tablets.
Elderly
Lower doses may be required; caution advised due to increased risk of side effects.
Renal_impairment
Use with caution and at reduced doses. Avoid in severe renal impairment.
How to Take
Take with food or milk to minimize gastrointestinal upset. Swallow the tablet whole with a glass of water.
Mechanism of Action
Ibuprofen works by inhibiting the production of prostaglandins, which are chemicals in the body that cause pain, inflammation, and fever. It achieves this by blocking the cyclooxygenase (COX-1 and COX-2) enzymes.
Pharmacokinetics
Onset
Within 30-60 minutes for analgesia.
Excretion
Primarily excreted in the urine as metabolites and their conjugates, with a small amount excreted in the feces.
Half life
Approximately 2-4 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract, peak plasma concentrations typically occur within 1-2 hours.
Metabolism
Extensively metabolized in the liver by oxidation and conjugation.
Side Effects
Contraindications
- Hypersensitivity to Ibuprofen or other NSAIDs (e.g., aspirin-induced asthma)
- Active gastrointestinal bleeding or peptic ulcer disease
- Severe heart failure, renal failure, or hepatic failure
- Third trimester of pregnancy
Drug Interactions
SSRIs
Increased risk of gastrointestinal bleeding.
Lithium
Increased plasma lithium levels, leading to toxicity.
Methotrexate
Increased plasma methotrexate levels, leading to toxicity.
ACE Inhibitors/Diuretics
Reduced antihypertensive effect and increased risk of renal impairment.
Anticoagulants (e.g., Warfarin)
Increased risk of bleeding.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include nausea, vomiting, abdominal pain, drowsiness, dizziness, tinnitus, and headache. Severe overdose may lead to central nervous system depression, convulsions, metabolic acidosis, and renal failure. Treatment is primarily symptomatic and supportive; gastric lavage or activated charcoal may be considered within an hour of ingestion.
Pregnancy & Lactation
Avoid in the third trimester of pregnancy due to risk of premature closure of the fetal ductus arteriosus and renal dysfunction. Use with caution in first and second trimesters only if clearly needed and benefits outweigh risks. Ibuprofen passes into breast milk in small amounts; generally considered compatible with breastfeeding, but consult a doctor.
Side Effects
Contraindications
- Hypersensitivity to Ibuprofen or other NSAIDs (e.g., aspirin-induced asthma)
- Active gastrointestinal bleeding or peptic ulcer disease
- Severe heart failure, renal failure, or hepatic failure
- Third trimester of pregnancy
Drug Interactions
SSRIs
Increased risk of gastrointestinal bleeding.
Lithium
Increased plasma lithium levels, leading to toxicity.
Methotrexate
Increased plasma methotrexate levels, leading to toxicity.
ACE Inhibitors/Diuretics
Reduced antihypertensive effect and increased risk of renal impairment.
Anticoagulants (e.g., Warfarin)
Increased risk of bleeding.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include nausea, vomiting, abdominal pain, drowsiness, dizziness, tinnitus, and headache. Severe overdose may lead to central nervous system depression, convulsions, metabolic acidosis, and renal failure. Treatment is primarily symptomatic and supportive; gastric lavage or activated charcoal may be considered within an hour of ingestion.
Pregnancy & Lactation
Avoid in the third trimester of pregnancy due to risk of premature closure of the fetal ductus arteriosus and renal dysfunction. Use with caution in first and second trimesters only if clearly needed and benefits outweigh risks. Ibuprofen passes into breast milk in small amounts; generally considered compatible with breastfeeding, but consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2 to 3 years from manufacturing date, check expiry date on packaging.
Availability
Pharmacies, supermarkets
Approval Status
Approved
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Ibuprofen has undergone extensive clinical trials demonstrating its efficacy and safety for pain, fever, and inflammation over decades. Ongoing research focuses on long-term effects and specific patient populations.
Lab Monitoring
- Renal function tests (e.g., serum creatinine, BUN) for long-term use
- Liver function tests (e.g., ALT, AST) for long-term use
- Complete blood count (CBC) for signs of GI bleeding with chronic use
Doctor Notes
- Assess patient's cardiovascular and gastrointestinal risk factors before prescribing long-term NSAID therapy.
- Consider lowest effective dose for shortest duration.
- Monitor renal function, liver enzymes, and blood pressure with chronic use.
Patient Guidelines
- Take with food or milk to reduce stomach upset.
- Do not exceed the recommended dose without consulting a doctor.
- Avoid alcohol while taking this medicine.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
May cause dizziness or drowsiness in some individuals; if affected, avoid driving or operating machinery.
Lifestyle Advice
- Maintain adequate hydration.
- Get sufficient rest, especially when recovering from illness or injury.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.