Med-Cal
Generic Name
Calcium Carbonate
Manufacturer
Wellbeing Inc.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| med cal 500 mg tablet | ৳ 2.00 | N/A |
Description
Overview of the medicine
Med-Cal 500 mg Tablet is a calcium supplement used to prevent and treat calcium deficiencies. It is vital for maintaining strong bones, healthy teeth, nerve function, and muscle contraction.
Uses & Indications
Dosage
Adults
Typically 500-1000 mg elemental calcium daily, usually in divided doses with meals. Refer to physician's advice.
Elderly
Similar to adult dosage, but often higher requirement due to age-related bone loss. Consult a doctor.
Renal_impairment
Use with caution and dose adjustment in severe renal impairment; monitor serum calcium levels closely. Consult a nephrologist.
How to Take
Administer orally, preferably with a meal to enhance absorption and reduce gastric upset. Do not chew or crush the tablet.
Mechanism of Action
Calcium is an essential mineral that plays a crucial role in various physiological processes, including bone formation, blood clotting, muscle contraction, and nerve impulse transmission. As a supplement, it provides exogenous calcium to maintain adequate levels in the body.
Pharmacokinetics
Onset
Gradual, as calcium levels are maintained over time.
Excretion
Excreted mainly via kidneys (urine) and feces, with some loss through sweat.
Half life
Systemic half-life is complex due to tight homeostatic control; bone half-life is several years. For acute doses, plasma half-life is minutes to hours.
Absorption
Absorption occurs primarily in the small intestine, efficiency varies (20-40%) and is enhanced by Vitamin D.
Metabolism
Not metabolized in the traditional sense; primarily integrated into bone tissue or circulated in the blood.
Side Effects
Contraindications
- Hypercalcemia (high calcium levels in blood)
- Severe hypercalciuria
- Hypersensitivity to calcium carbonate or any component of the formulation
- Severe renal impairment (unless on dialysis and under strict medical supervision)
Drug Interactions
Bisphosphonates
Calcium can reduce the absorption of bisphosphonates. Take calcium at a different time of day.
Thiazide diuretics
May decrease calcium excretion, increasing the risk of hypercalcemia.
Tetracycline and Quinolone antibiotics
Calcium can bind to these antibiotics, reducing their absorption. Administer at least 2-4 hours apart.
Thyroid hormones (e.g., Levothyroxine)
Calcium can interfere with the absorption of thyroid hormones. Administer at least 4 hours apart.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include severe constipation, nausea, vomiting, confusion, polydipsia, polyuria, and in severe cases, cardiac arrhythmias. Management involves discontinuing calcium, hydration, and medical support.
Pregnancy & Lactation
Calcium is essential during pregnancy and lactation. This supplement is generally considered safe when taken at recommended doses. Consult a doctor before use.
Side Effects
Contraindications
- Hypercalcemia (high calcium levels in blood)
- Severe hypercalciuria
- Hypersensitivity to calcium carbonate or any component of the formulation
- Severe renal impairment (unless on dialysis and under strict medical supervision)
Drug Interactions
Bisphosphonates
Calcium can reduce the absorption of bisphosphonates. Take calcium at a different time of day.
Thiazide diuretics
May decrease calcium excretion, increasing the risk of hypercalcemia.
Tetracycline and Quinolone antibiotics
Calcium can bind to these antibiotics, reducing their absorption. Administer at least 2-4 hours apart.
Thyroid hormones (e.g., Levothyroxine)
Calcium can interfere with the absorption of thyroid hormones. Administer at least 4 hours apart.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include severe constipation, nausea, vomiting, confusion, polydipsia, polyuria, and in severe cases, cardiac arrhythmias. Management involves discontinuing calcium, hydration, and medical support.
Pregnancy & Lactation
Calcium is essential during pregnancy and lactation. This supplement is generally considered safe when taken at recommended doses. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months from the date of manufacture.
Availability
Pharmacies, supermarkets, online stores
Approval Status
Approved for OTC use
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Numerous clinical trials have established the efficacy of calcium supplementation in preventing and managing osteoporosis and calcium deficiencies. Specific trials for 'Med-Cal' are typically bioavailability studies.
Lab Monitoring
- Serum calcium levels (especially in patients with renal impairment or taking other calcium-affecting medications)
- Renal function (e.g., creatinine, eGFR) in long-term use or in predisposed individuals
Doctor Notes
- Advise patients to report any symptoms of hypercalcemia (e.g., excessive thirst, frequent urination, muscle weakness).
- Remind patients about potential drug interactions, especially with antibiotics and thyroid hormones.
Patient Guidelines
- Take with a full glass of water, preferably with a meal.
- Do not exceed the recommended dose without consulting a doctor.
- Inform your doctor about all other medications you are taking, especially antibiotics, thyroid hormones, and diuretics.
- Maintain adequate fluid intake throughout the day.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Med-Cal 500 mg Tablet is not known to affect the ability to drive or operate machinery.
Lifestyle Advice
- Ensure a balanced diet rich in calcium and Vitamin D.
- Engage in regular weight-bearing exercise to support bone health.
- Avoid excessive consumption of alcohol and caffeine, which can hinder calcium absorption.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.