Mederma Advanced
Generic Name
Cepalin Botanical Extract, Allantoin, Panthenol (Scar Treatment Gel)
Manufacturer
HRA Pharma (a company of Perrigo)
Country
USA
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| mederma advanced 10 gm gel | ৳ 920.00 | N/A |
Description
Overview of the medicine
Mederma Advanced Scar Gel is a topical treatment formulated to improve the overall appearance, color, and texture of scars. It is effective on new and old scars, resulting from acne, surgery, injuries, burns, and other causes. The unique triple-action formula penetrates beneath the skin surface to seal in moisture, stimulate collagen production, and renew skin cells.
Uses & Indications
Dosage
Adults
Apply a thin layer to the scar and massage gently until absorbed, once daily.
Elderly
Same as adult dosage.
Renal_impairment
No dosage adjustment needed as it's a topical product with minimal systemic absorption.
How to Take
For external use only. Apply a thin layer to the scar and massage gently until absorbed, once daily.
Mechanism of Action
The triple-action formula of Mederma Advanced combines Cepalin botanical extract, Allantoin, and Panthenol. Cepalin is believed to regulate collagen production, reduce inflammation, and improve skin elasticity. Allantoin acts as a skin protectant, promotes cell proliferation, and has moisturizing properties. Panthenol (Pro-Vitamin B5) helps in skin hydration and repair. Together, these ingredients work to soften, smooth, and reduce the discoloration of scars, aiding in the remodeling process of the skin.
Pharmacokinetics
Onset
Visible improvement typically within 14 days for new scars, 3-6 months for old scars.
Excretion
Not significantly absorbed systemically, therefore systemic excretion routes are not relevant.
Half life
Not applicable for a topical, locally acting product.
Absorption
Minimal systemic absorption expected. Primarily local action.
Metabolism
Primarily local enzymatic breakdown on the skin surface.
Side Effects
Contraindications
- Hypersensitivity to any component of the gel
- Open wounds or broken skin (should be applied only after the wound has closed)
Drug Interactions
Other topical products
No known specific interactions, but generally advisable to avoid applying multiple topical products simultaneously on the same area unless directed by a healthcare professional.
Storage
Store at room temperature (15-30°C), away from direct sunlight and excessive heat. Do not freeze. Keep out of reach of children.
Overdose
Overdose from topical application is highly unlikely due to minimal systemic absorption. In case of accidental ingestion, seek medical advice.
Pregnancy & Lactation
Generally considered safe for topical use during pregnancy and lactation, as systemic absorption is minimal. However, consult a healthcare professional before use.
Side Effects
Contraindications
- Hypersensitivity to any component of the gel
- Open wounds or broken skin (should be applied only after the wound has closed)
Drug Interactions
Other topical products
No known specific interactions, but generally advisable to avoid applying multiple topical products simultaneously on the same area unless directed by a healthcare professional.
Storage
Store at room temperature (15-30°C), away from direct sunlight and excessive heat. Do not freeze. Keep out of reach of children.
Overdose
Overdose from topical application is highly unlikely due to minimal systemic absorption. In case of accidental ingestion, seek medical advice.
Pregnancy & Lactation
Generally considered safe for topical use during pregnancy and lactation, as systemic absorption is minimal. However, consult a healthcare professional before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date (check packaging for exact date).
Availability
Pharmacies, Drugstores, Online Retailers
Approval Status
Generally Recognized As Safe (GRAS) for ingredients, OTC product
Patent Status
Proprietary formulation, individual ingredients off-patent
Clinical Trials
Mederma products have been subjects of clinical studies demonstrating efficacy in improving scar appearance, color, and texture. Studies often involve patient self-assessment and physician evaluation over several weeks to months.
Lab Monitoring
- None required for routine use.
Doctor Notes
- Advise patients on consistent application for optimal results.
- Emphasize sun protection for treated scars to prevent hyperpigmentation.
- Clarify that results vary depending on scar type, age, and individual healing capacity.
Patient Guidelines
- Use on closed wounds only.
- Consistency is key for best results.
- Protect treated scars from sun exposure.
- Avoid contact with eyes, mouth, and mucous membranes.
- If irritation occurs, discontinue use and consult a doctor.
Missed Dose Advice
If a dose is missed, simply apply the next dose at the regular time. Do not apply extra gel to make up for a missed dose.
Driving Precautions
None, as it's a topical product and does not cause systemic effects that impair driving.
Lifestyle Advice
- Maintain good hydration.
- Eat a balanced diet to support skin healing.
- Avoid activities that might stretch or damage the scar during the healing process.
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