Medibion
Generic Name
Thiamine Hydrochloride + Pyridoxine Hydrochloride + Cyanocobalamin
Manufacturer
Merck KGaA
Country
Germany
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| medibion 100 mg tablet | ৳ 8.00 | ৳ 80.00 |
Description
Overview of the medicine
Medibion 100 mg Tablet is a vitamin B complex supplement consisting of Thiamine, Pyridoxine, and Cyanocobalamin. It is used to treat vitamin B deficiencies and nerve disorders.
Uses & Indications
Dosage
Adults
Typically 1 tablet daily or as directed by physician.
Elderly
Same as adults, unless severe renal or hepatic impairment exists.
Renal_impairment
Dosage adjustment may be required in significant renal impairment, but generally safe for water-soluble vitamins.
How to Take
Take orally, with or without food.
Mechanism of Action
Thiamine plays a crucial role in carbohydrate metabolism and proper nerve function. Pyridoxine participates in amino acid metabolism and neurotransmitter synthesis. Cyanocobalamin is essential for red blood cell production, DNA synthesis, and nerve myelination.
Pharmacokinetics
Onset
Onset of action varies depending on the severity of the deficiency.
Excretion
Mainly excreted via urine, mostly unchanged or as metabolites.
Half life
Thiamine plasma half-life is short, tissue half-life 9-18 days. Pyridoxine half-life 15-20 days. Cyanocobalamin half-life approximately 6 days.
Absorption
Readily absorbed from the gastrointestinal tract.
Metabolism
Primarily metabolized in the liver.
Side Effects
Contraindications
- •Hypersensitivity to any component of the medication
Drug Interactions
Alcohol
Can interfere with vitamin B absorption.
Levodopa
Pyridoxine may decrease the effectiveness of Levodopa (if used without carbidopa).
Loop Diuretics
Long-term use may cause thiamine deficiency.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Due to being water-soluble vitamins, the risk of severe toxicity from overdose is low. However, very high doses of Pyridoxine taken long-term can cause peripheral neuropathy. Gastrointestinal discomfort may occur.
Pregnancy & Lactation
Generally safe and often recommended during pregnancy and lactation, but consult a doctor for appropriate dosage.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years
Availability
Pharmacies, drugstores, supermarkets
Approval Status
Approved by relevant health authorities
Patent Status
Generic / Off-patent
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine
More Medicines
Explore other medicines you might be interested in