Meflocin
Generic Name
Moxifloxacin 0.3% Ophthalmic Solution
Manufacturer
Acme Laboratories Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| meflocin 03 eye drop | ৳ 70.00 | N/A |
Description
Overview of the medicine
Meflocin-03 Eye Drop contains Moxifloxacin 0.3%, a fourth-generation fluoroquinolone antibiotic, used to treat bacterial infections of the eye.
Uses & Indications
Dosage
Adults
Instill one drop in the affected eye(s) 3 times a day for 7 days.
Elderly
No dosage adjustment required.
Renal_impairment
No dosage adjustment required as systemic absorption is minimal.
How to Take
For ophthalmic use only. Tilt head back, pull down lower eyelid, and instill one drop into the conjunctival sac. Avoid touching the dropper tip to the eye or any other surface.
Mechanism of Action
Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination, leading to bacterial cell death.
Pharmacokinetics
Onset
Clinical improvement often observed within a few days.
Excretion
Mainly excreted renally if systemically absorbed; otherwise, washed out from the eye with tears.
Half life
Ocular tissue half-life is short, systemic half-life around 12-15 hours (though systemic exposure is minimal from eye drops).
Absorption
Following topical ophthalmic administration, Moxifloxacin is absorbed into the ocular tissues. Systemic absorption is minimal.
Metabolism
Minimal metabolism occurs in ocular tissues. Primarily excreted unchanged if absorbed systemically.
Side Effects
Contraindications
- Hypersensitivity to Moxifloxacin or other quinolones, or to any component of the formulation.
Drug Interactions
Other ophthalmic preparations
If using other ophthalmic medications, wait at least 5-10 minutes between applications.
Storage
Store at room temperature (below 30°C). Do not freeze. Keep out of reach of children.
Overdose
An ophthalmic overdose is unlikely to cause systemic toxicity. In case of accidental ingestion or excessive ocular application, flush the eyes with lukewarm water.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution is advised during lactation as moxifloxacin is excreted in human milk after systemic administration; however, systemic exposure from ophthalmic drops is very low.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24 months (unopened). Discard 28 days after opening.
Availability
Pharmacies, Hospitals, Clinics
Approval Status
Approved by DGDA
Patent Status
Generic Available
Clinical Trials
Moxifloxacin 0.3% ophthalmic solution has undergone extensive clinical trials demonstrating its efficacy and safety for treating bacterial conjunctivitis.
Lab Monitoring
- No routine lab monitoring required for topical ophthalmic use.
Doctor Notes
- Advise patients to maintain strict hygiene when applying eye drops.
- Monitor for signs of superinfection or allergic reaction.
Patient Guidelines
- Complete the full course of treatment, even if symptoms improve.
- Remove contact lenses before application and wait at least 15 minutes before reinserting them.
- Do not share your eye drops with anyone else.
Missed Dose Advice
If a dose is missed, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose.
Driving Precautions
May cause temporary blurred vision or discomfort after application. Avoid driving or operating machinery until vision is clear.
Lifestyle Advice
- Maintain good eye hygiene to prevent re-infection.
- Avoid rubbing your eyes excessively.
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.