melizin
Generic Name
Meclizine Hydrochloride
Manufacturer
Generic Pharmaceutical Company
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| melizin 50 mg tablet | ৳ 2.50 | ৳ 25.00 |
Description
Overview of the medicine
Melizin 50 mg Tablet is an antihistamine primarily used to prevent and treat symptoms of motion sickness, vertigo (dizziness), nausea, and vomiting.
Uses & Indications
Dosage
Adults
For motion sickness: 25-50 mg orally 1 hour before travel; may be repeated every 24 hours as needed. For vertigo: 25-100 mg daily in divided doses.
Elderly
Start with a lower dose (e.g., 25 mg daily) due to increased sensitivity to anticholinergic effects and potential for sedation.
Renal_impairment
No specific dosage adjustment is generally required, but use with caution in severe renal impairment.
How to Take
Take orally with or without food. To prevent motion sickness, take it 1 hour before travel.
Mechanism of Action
Meclizine works by blocking H1-histamine receptors, and has central anticholinergic effects that reduce excitability of the labyrinth and vestibular-cerebellar pathways, thereby reducing motion sickness and vertigo symptoms.
Pharmacokinetics
Onset
Onset of action within approximately 1 hour.
Excretion
Excreted mainly in the urine and feces.
Half life
Plasma half-life ranges from 6 to 12 hours (may extend up to 24 hours).
Absorption
Well absorbed after oral administration.
Metabolism
Primarily metabolized in the liver.
Side Effects
Contraindications
- •Hypersensitivity to Meclizine or any component of the formulation
- •Acute asthmatic attack
- •Prostatic hypertrophy
- •Angle-closure glaucoma
Drug Interactions
Anticholinergic drugs
May potentiate anticholinergic effects (e.g., dry mouth, blurred vision, urinary retention).
CNS Depressants (e.g., alcohol, sedatives, tranquilizers)
May enhance sedative effects.
Storage
Store below 25°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include excessive drowsiness, confusion, ataxia, hallucinations, seizures, and anticholinergic effects. Management is supportive, including gastric lavage or activated charcoal.
Pregnancy & Lactation
Pregnancy Category B. Use with caution during lactation as it may be excreted in breast milk and cause drowsiness in the infant.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years from manufacturing date.
Availability
Available in pharmacies and hospitals
Approval Status
Approved by regulatory authorities
Patent Status
Off-patent (Generic available)
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine
More Medicines
Explore other medicines you might be interested in