Mexilyt
Generic Name
Cyproheptadine Hydrochloride
Manufacturer
Acme Laboratories Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| mexilyt 4 mg syrup | ৳ 18.06 | N/A |
Description
Overview of the medicine
Mexilyt 4 mg Syrup contains Cyproheptadine Hydrochloride, an antihistamine with antiserotonergic and appetite-stimulating properties. It is used to treat various allergic conditions and as an appetite stimulant.
Uses & Indications
Dosage
Adults
Adults: 4 mg (5 ml) three times daily, up to a maximum of 32 mg (40 ml) daily.
Elderly
Elderly: Lower initial doses may be required (e.g., 2 mg (2.5 ml) twice daily), adjust based on response.
Renal_impairment
Renal impairment: Use with caution; dosage adjustment may be necessary. Not recommended in severe impairment.
How to Take
Orally, with or without food. Use a measuring spoon or cup for accurate dosing.
Mechanism of Action
Cyproheptadine acts as a potent H1-receptor antagonist, blocking the effects of histamine. It also possesses serotonin antagonist activity, which is believed to contribute to its appetite-stimulating effects. Additionally, it has some anticholinergic and local anesthetic properties.
Pharmacokinetics
Onset
Within 15-30 minutes.
Excretion
Mainly excreted in urine as metabolites, with some in feces.
Half life
Approximately 8 hours.
Absorption
Well absorbed from the gastrointestinal tract.
Metabolism
Extensively metabolized in the liver, primarily via glucuronidation.
Side Effects
Contraindications
- •Hypersensitivity to cyproheptadine or any component of the formulation
- •Acute asthma attack
- •Narrow-angle glaucoma
- •Urinary retention
- •Peptic ulcer
- •Symptomatic prostatic hypertrophy
- •Concomitant use with MAO inhibitors
- •Newborns or premature infants
Drug Interactions
MAO inhibitors
Prolonged and intensified anticholinergic effects of antihistamines.
Anticholinergics
Potentiated anticholinergic effects.
CNS depressants (alcohol, sedatives, hypnotics)
Increased CNS depression.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children. Do not freeze.
Overdose
Symptoms may include drowsiness, dizziness, ataxia, blurred vision, dry mouth, fixed dilated pupils, flushing, gastrointestinal upset, urinary retention, and in severe cases, seizures, coma, and respiratory depression. Treatment is symptomatic and supportive. Gastric lavage or activated charcoal may be considered if recent ingestion. Do not use stimulants.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Excreted in breast milk, avoid during lactation due to potential for sedation in infant.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date when stored properly.
Availability
Pharmacies, Hospitals
Approval Status
Approved
Patent Status
Generic available
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Global Brand Names
International brand names for this medicine
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