MIC-2-W
Generic Name
Miconazole Nitrate 2% w/w
Manufacturer
Acme Pharmaceuticals (Example)
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| mic 2 w cream | ৳ 35.00 | N/A |
Description
Overview of the medicine
MIC-2-W Cream contains Miconazole Nitrate 2% w/w, an antifungal medication used to treat various skin infections caused by fungi. It works by preventing the growth of fungi.
Uses & Indications
Dosage
Adults
Apply a thin layer to the affected area and surrounding skin twice daily (morning and evening).
Elderly
No specific dosage adjustment required.
Renal_impairment
No specific dosage adjustment required.
How to Take
For external use only. Wash and dry the affected area thoroughly before application. Apply a thin layer and rub gently. Wash hands after use.
Mechanism of Action
Miconazole works by inhibiting the biosynthesis of ergosterol, an essential component of the fungal cell membrane. This leads to increased cell membrane permeability, leakage of cellular contents, and eventual death of the fungal cell.
Pharmacokinetics
Onset
Symptomatic relief usually begins within a few days of treatment. Complete clearance may take 2-4 weeks.
Excretion
Excreted predominantly in feces, with a small amount in urine.
Half life
Systemic half-life not clinically relevant due to minimal absorption.
Absorption
Minimally absorbed through the skin after topical application. Systemic absorption is very low.
Metabolism
What little is absorbed is metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to miconazole or any component of the cream
- Not for ophthalmic or oral use
Drug Interactions
Warfarin
May enhance the anticoagulant effect of warfarin, leading to increased bleeding risk.
Phenytoin
May increase phenytoin levels.
Storage
Store below 30°C in a dry place, away from light and moisture. Do not freeze.
Overdose
Accidental ingestion or excessive topical application is unlikely to cause systemic toxicity due to poor absorption. In case of accidental ingestion, symptomatic and supportive measures are recommended.
Pregnancy & Lactation
Use with caution during pregnancy and lactation. Consult a doctor before use. Systemic absorption is minimal, but risks and benefits should be weighed.
Side Effects
Contraindications
- Hypersensitivity to miconazole or any component of the cream
- Not for ophthalmic or oral use
Drug Interactions
Warfarin
May enhance the anticoagulant effect of warfarin, leading to increased bleeding risk.
Phenytoin
May increase phenytoin levels.
Storage
Store below 30°C in a dry place, away from light and moisture. Do not freeze.
Overdose
Accidental ingestion or excessive topical application is unlikely to cause systemic toxicity due to poor absorption. In case of accidental ingestion, symptomatic and supportive measures are recommended.
Pregnancy & Lactation
Use with caution during pregnancy and lactation. Consult a doctor before use. Systemic absorption is minimal, but risks and benefits should be weighed.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months
Availability
Pharmacies, drug stores
Approval Status
Approved by major regulatory bodies (e.g., FDA, DGDA)
Patent Status
Patent expired
WHO Essential Medicine
YesClinical Trials
Numerous clinical trials have established the efficacy and safety of topical miconazole for fungal skin infections.
Lab Monitoring
- No specific laboratory monitoring required for topical miconazole.
Doctor Notes
- Advise patients to complete the full course of treatment.
- Monitor for signs of hypersensitivity reactions.
- Educate on proper hygiene to prevent recurrence.
Patient Guidelines
- Use the cream for the full prescribed duration, even if symptoms improve.
- Avoid contact with eyes, nose, and mouth.
- Do not cover the treated area with an occlusive dressing unless advised by a doctor.
- Maintain good hygiene to prevent reinfection.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose.
Driving Precautions
No known effects on ability to drive or operate machinery.
Lifestyle Advice
- Wear loose-fitting clothing to allow air circulation.
- Keep affected areas clean and dry.
- Avoid sharing towels and personal items.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.