Micoplex-B
Generic Name
B-Complex Vitamins (e.g., Pyridoxine HCl 5 mg and other B vitamins)
Manufacturer
Acme Laboratories Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| micoplex b 5 mg tablet | ৳ 0.43 | N/A |
Description
Overview of the medicine
Micoplex-B 5 mg Tablet is a B-complex vitamin preparation containing several essential B vitamins. It is used to prevent and treat vitamin B deficiencies and to support overall health, nerve function, and metabolism. The '5 mg' typically refers to the strength of Pyridoxine (Vitamin B6) within the complex.
Uses & Indications
Dosage
Adults
Usually 1 tablet daily, or as directed by a physician. In severe deficiency, dosage may be increased.
Elderly
No specific dosage adjustment needed unless underlying renal impairment. Consult physician.
Renal_impairment
Generally safe, but consult a physician, especially with severe impairment, as some B vitamins are renally excreted.
How to Take
Take orally, with or without food. It can be taken with meals to minimize gastrointestinal upset.
Mechanism of Action
B vitamins act as coenzymes in various metabolic processes, including carbohydrate, fat, and protein metabolism. They are essential for cellular energy production, DNA synthesis, nerve function, and red blood cell formation. Pyridoxine (B6) is crucial for amino acid metabolism and neurotransmitter synthesis.
Pharmacokinetics
Onset
Effects are typically seen within days to weeks with regular use, as deficiencies are corrected.
Excretion
Excreted primarily via the kidneys in urine, often resulting in bright yellow urine due to riboflavin.
Half life
Half-lives vary for individual B vitamins, generally ranging from hours to days.
Absorption
Water-soluble B vitamins are readily absorbed from the gastrointestinal tract, primarily in the small intestine.
Metabolism
Metabolized in the liver. Excess water-soluble vitamins are not stored extensively.
Side Effects
Contraindications
- Known hypersensitivity to any component of the formulation
Drug Interactions
Levodopa
Pyridoxine (Vitamin B6) can reduce the effectiveness of levodopa (used in Parkinson's disease) when levodopa is not combined with a decarboxylase inhibitor. However, this interaction is less common with modern levodopa preparations.
Phenobarbital/Phenytoin
High doses of some B vitamins might interfere with phenobarbital or phenytoin levels, although typically not clinically significant for standard B-complex doses.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
B-complex vitamins are water-soluble, and excess amounts are usually excreted. However, very high doses of certain individual B vitamins (e.g., Pyridoxine at extremely high doses) can cause adverse effects like peripheral neuropathy. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe and often recommended during pregnancy and lactation, as B vitamins are crucial for fetal development and maternal health. However, always consult a physician before use.
Side Effects
Contraindications
- Known hypersensitivity to any component of the formulation
Drug Interactions
Levodopa
Pyridoxine (Vitamin B6) can reduce the effectiveness of levodopa (used in Parkinson's disease) when levodopa is not combined with a decarboxylase inhibitor. However, this interaction is less common with modern levodopa preparations.
Phenobarbital/Phenytoin
High doses of some B vitamins might interfere with phenobarbital or phenytoin levels, although typically not clinically significant for standard B-complex doses.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
B-complex vitamins are water-soluble, and excess amounts are usually excreted. However, very high doses of certain individual B vitamins (e.g., Pyridoxine at extremely high doses) can cause adverse effects like peripheral neuropathy. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe and often recommended during pregnancy and lactation, as B vitamins are crucial for fetal development and maternal health. However, always consult a physician before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from the date of manufacture.
Availability
Pharmacies, drugstores
Approval Status
Approved (typically OTC)
Patent Status
Generic
Clinical Trials
Extensive clinical data supports the efficacy of B vitamins in preventing and treating deficiencies. Specific trials for this brand typically focus on bioavailability and manufacturing quality rather than novel indications.
Lab Monitoring
- Not typically required for routine use. In cases of suspected severe deficiency, specific vitamin levels might be tested.
Doctor Notes
- Crucial for patients with conditions causing B vitamin malabsorption (e.g., celiac disease, bariatric surgery).
- Consider for patients with increased metabolic demands (e.g., athletes, pregnant women, hyperthyroidism).
- Educate patients about urine discoloration due to riboflavin to avoid unnecessary concern.
Patient Guidelines
- Take exactly as directed by your physician or as indicated on the label.
- Do not exceed the recommended dose without consulting a healthcare professional.
- Inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Micoplex-B is not known to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in fruits, vegetables, and whole grains to ensure adequate vitamin intake.
- Avoid excessive alcohol consumption, as it can deplete B vitamin stores.
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