Mirolast
Generic Name
Olopatadine Hydrochloride 0.1% Ophthalmic Solution
Manufacturer
Opsonin Pharma Limited
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| mirolast 01 eye drop | ৳ 75.00 | N/A |
Description
Overview of the medicine
Mirolast-01 Eye Drop contains Olopatadine Hydrochloride 0.1%, an ophthalmic solution used to treat ocular itching associated with allergic conjunctivitis.
Uses & Indications
Dosage
Adults
Instill 1 drop in each affected eye twice a day, at an interval of 6 to 8 hours.
Elderly
No specific dosage adjustment is necessary for elderly patients.
Renal_impairment
No dosage adjustment required due to minimal systemic absorption.
How to Take
For ophthalmic use only. Tilt head back, pull down the lower eyelid, instill one drop into the conjunctival sac. Avoid touching the dropper tip to the eye or any other surface to prevent contamination.
Mechanism of Action
It acts as a selective histamine H1-receptor antagonist and mast cell stabilizer, thereby reducing ocular itching and redness by blocking histamine release and inhibiting mast cell degranulation.
Pharmacokinetics
Onset
Rapid onset of action, typically within minutes of administration.
Excretion
Primarily excreted unchanged in the urine.
Half life
Systemic half-life is approximately 3 hours, but ocular exposure is largely localized.
Absorption
Minimal systemic absorption following ophthalmic administration. Peak plasma concentrations are typically reached within 30 minutes to 1 hour.
Metabolism
Primarily renal excretion of unchanged drug. Minimal metabolism occurs.
Side Effects
Contraindications
- Hypersensitivity to olopatadine hydrochloride or any component of the formulation.
Drug Interactions
Systemic Medications
Due to minimal systemic absorption, clinically significant drug interactions are unlikely.
Storage
Store at room temperature (below 30°C). Protect from light. Do not freeze. Keep out of reach of children.
Overdose
Ocular overdose is unlikely. If accidentally ingested, supportive treatment should be initiated.
Pregnancy & Lactation
Pregnancy Category C. Use only if the potential benefit justifies the potential risk to the fetus. Caution should be exercised when administered to a nursing mother.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years unopened. Discard 28 days after opening.
Availability
Available in pharmacies and hospitals
Approval Status
Approved by regulatory authorities (e.g., DGDA)
Patent Status
Generic available, patent expired for original formulation
Clinical Trials
Extensive clinical trials have demonstrated the efficacy and safety of olopatadine for the treatment of ocular itching associated with allergic conjunctivitis.
Lab Monitoring
- No routine laboratory monitoring is required for ophthalmic olopatadine.
Doctor Notes
- Advise patients on proper instillation technique to maximize efficacy and minimize side effects.
- Educate patients that Mirolast-01 provides rapid relief of ocular itching.
- Remind patients about contact lens precautions.
Patient Guidelines
- Remove contact lenses before use and wait at least 10 minutes before reinserting them.
- Do not share eye drops with others to avoid contamination.
- Follow the prescribed dosage and administration instructions carefully.
Missed Dose Advice
If a dose is missed, apply it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause temporary blurred vision or other visual disturbances. Exercise caution when driving or operating machinery until vision is clear.
Lifestyle Advice
- Avoid exposure to known allergens if possible.
- Maintain good eye hygiene.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.