Momespray
Generic Name
Mometasone Furoate Nasal Spray 50 mcg
Manufacturer
Leading Pharmaceutical Company
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| momespray 50 mcg nasal spray | ৳ 250.00 | N/A |
Description
Overview of the medicine
Momespray 50 mcg Nasal Spray contains Mometasone Furoate, a synthetic corticosteroid used to relieve symptoms of seasonal and perennial allergic rhinitis, and for the treatment of nasal polyps.
Uses & Indications
Dosage
Adults
Allergic Rhinitis: Two sprays (50 mcg each) into each nostril once daily. Nasal Polyps: Two sprays (50 mcg each) into each nostril twice daily.
Elderly
No specific dosage adjustment is required for elderly patients.
Renal_impairment
No specific dosage adjustment is required due to very low systemic absorption.
How to Take
For nasal use only. Shake the bottle well before each use. Prime the pump before the first use or if the spray has not been used for more than one week. Gently blow your nose to clear the nostrils before administration.
Mechanism of Action
Mometasone Furoate is a potent glucocorticoid with anti-inflammatory properties. It reduces the release of inflammatory mediators (e.g., histamines, leukotrienes) and inhibits the migration of inflammatory cells, thereby decreasing inflammation and allergic symptoms in the nasal passages.
Pharmacokinetics
Onset
Clinical improvement often seen within 1-2 days, full effect may take 1-2 weeks.
Excretion
Primarily excreted in the feces and, to a lesser extent, in the urine.
Half life
Systemic half-life is approximately 5.8 hours (for absorbed portion).
Absorption
Very low systemic absorption from nasal administration (less than 0.1% bioavailable).
Metabolism
Extensively metabolized in the liver by CYP3A4.
Side Effects
Contraindications
- Hypersensitivity to Mometasone Furoate or any component of the spray.
- Untreated localized infection involving the nasal mucosa.
- Recent nasal surgery or trauma, until healing has occurred.
Drug Interactions
Strong CYP3A4 inhibitors (e.g., Ketoconazole)
Co-administration with strong CYP3A4 inhibitors may increase systemic exposure to mometasone furoate, though this is usually not clinically significant due to low nasal absorption.
Storage
Store below 30°C. Protect from light. Do not freeze.
Overdose
Acute overdose is unlikely with nasal administration due to very low systemic absorption. Chronic excessive use may lead to signs and symptoms of hypercorticism. Treatment should be supportive, with gradual tapering of the drug if chronic high doses were used.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is unknown if Mometasone Furoate is excreted in human milk; use with caution in nursing mothers.
Side Effects
Contraindications
- Hypersensitivity to Mometasone Furoate or any component of the spray.
- Untreated localized infection involving the nasal mucosa.
- Recent nasal surgery or trauma, until healing has occurred.
Drug Interactions
Strong CYP3A4 inhibitors (e.g., Ketoconazole)
Co-administration with strong CYP3A4 inhibitors may increase systemic exposure to mometasone furoate, though this is usually not clinically significant due to low nasal absorption.
Storage
Store below 30°C. Protect from light. Do not freeze.
Overdose
Acute overdose is unlikely with nasal administration due to very low systemic absorption. Chronic excessive use may lead to signs and symptoms of hypercorticism. Treatment should be supportive, with gradual tapering of the drug if chronic high doses were used.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is unknown if Mometasone Furoate is excreted in human milk; use with caution in nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years unopened; 2 months after first opening.
Availability
Available in pharmacies and hospitals
Approval Status
Approved by major regulatory bodies (e.g., FDA, DGDA)
Patent Status
Generic available
Clinical Trials
Extensive clinical trials have demonstrated the efficacy and safety of Mometasone Furoate Nasal Spray in the treatment of seasonal and perennial allergic rhinitis and nasal polyps in various age groups, supporting its regulatory approval and widespread use.
Lab Monitoring
- Regular monitoring of growth velocity in pediatric patients receiving prolonged treatment.
- Intraocular pressure monitoring in patients with a history of glaucoma or cataracts, or those on prolonged high doses.
Doctor Notes
- Counsel patients on correct nasal spray technique to ensure optimal drug delivery and minimize local side effects.
- Advise patients on the importance of regular use for sustained symptom control, as effects may not be immediate and optimal benefits achieved over several days to weeks.
- Monitor pediatric patients receiving long-term treatment for growth velocity, and consider lowest effective dose.
Patient Guidelines
- Read the patient instruction leaflet carefully before use.
- Shake the bottle well before each use.
- Prime the pump before the first use or if not used for 7 days.
- Do not spray into your eyes or mouth.
- Avoid sharing your nasal spray with others to prevent the spread of germs.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Mometasone furoate nasal spray is not expected to affect the ability to drive or operate machinery.
Lifestyle Advice
- Identify and avoid known allergens.
- Maintain good nasal hygiene.
- Use regularly as prescribed for best results, even if symptoms improve.
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Global Brand Names
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