Monocal
Generic Name
Calcium Carbonate
Manufacturer
Local Pharmaceutical Company
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| monocal 500 mg tablet | ৳ 4.01 | ৳ 40.10 |
Description
Overview of the medicine
Monocal 500 mg Tablet is a mineral supplement containing Calcium Carbonate. It is used to prevent and treat calcium deficiencies, support bone health, and in some cases, as an antacid.
Uses & Indications
Dosage
Adults
For calcium supplementation: 500-1000 mg daily, typically in divided doses with meals. For antacid: 500-1500 mg as needed.
Elderly
Similar to adult dosage, but may require careful monitoring of calcium levels due to potential renal impairment.
Renal_impairment
Use with caution and monitor calcium levels; dosage adjustment may be necessary to avoid hypercalcemia.
How to Take
Take orally with water, preferably with meals to enhance absorption and reduce gastrointestinal upset. If used as an antacid, chew tablets thoroughly before swallowing.
Mechanism of Action
Calcium is an essential mineral necessary for many bodily functions, including bone formation, nerve transmission, muscle contraction, and blood clotting. Calcium carbonate acts by providing calcium ions, which are absorbed and utilized by the body.
Pharmacokinetics
Onset
Within hours for calcium supplementation; immediate for antacid effect.
Excretion
Unabsorbed calcium is excreted in feces. Absorbed calcium is primarily excreted via kidneys in urine, regulated by hormones.
Half life
The body tightly regulates calcium levels; absorbed calcium is incorporated into bone or excreted.
Absorption
Approximately 20-30% of ingested calcium carbonate is absorbed, primarily in the small intestine. Absorption is enhanced by Vitamin D.
Metabolism
Not metabolized in the traditional sense; ionized calcium is the active form.
Side Effects
Contraindications
- Hypercalcemia (high calcium levels)
- Severe hypercalciuria (high calcium in urine)
- Nephrolithiasis (kidney stones)
- Hypophosphatemia
Drug Interactions
Levothyroxine
Calcium may impair levothyroxine absorption. Separate administration by at least 4 hours.
Bisphosphonates
Calcium can interfere with bisphosphonate absorption. Take calcium at a different time of day.
Iron supplements
Calcium may reduce iron absorption. Separate administration by at least 2 hours.
Thiazide diuretics
May increase risk of hypercalcemia.
Tetracyclines & Fluoroquinolones
Calcium can chelate these antibiotics, reducing their absorption. Take calcium at least 2-4 hours before or after these medications.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include severe hypercalcemia (nausea, vomiting, constipation, confusion, muscle weakness, kidney dysfunction). Treatment involves discontinuing calcium, hydration, and medical management of hypercalcemia.
Pregnancy & Lactation
Calcium is essential during pregnancy and lactation. This medicine can be used as a supplement if dietary intake is insufficient, under medical advice. Do not exceed recommended doses.
Side Effects
Contraindications
- Hypercalcemia (high calcium levels)
- Severe hypercalciuria (high calcium in urine)
- Nephrolithiasis (kidney stones)
- Hypophosphatemia
Drug Interactions
Levothyroxine
Calcium may impair levothyroxine absorption. Separate administration by at least 4 hours.
Bisphosphonates
Calcium can interfere with bisphosphonate absorption. Take calcium at a different time of day.
Iron supplements
Calcium may reduce iron absorption. Separate administration by at least 2 hours.
Thiazide diuretics
May increase risk of hypercalcemia.
Tetracyclines & Fluoroquinolones
Calcium can chelate these antibiotics, reducing their absorption. Take calcium at least 2-4 hours before or after these medications.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include severe hypercalcemia (nausea, vomiting, constipation, confusion, muscle weakness, kidney dysfunction). Treatment involves discontinuing calcium, hydration, and medical management of hypercalcemia.
Pregnancy & Lactation
Calcium is essential during pregnancy and lactation. This medicine can be used as a supplement if dietary intake is insufficient, under medical advice. Do not exceed recommended doses.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2 to 3 years from manufacturing date.
Availability
Pharmacies, drugstores, supermarkets
Approval Status
Approved by relevant regulatory authorities (e.g., FDA, DGDA)
Patent Status
Generic
WHO Essential Medicine
YesClinical Trials
Extensively studied and widely used for calcium supplementation and antacid purposes. Numerous clinical trials support its efficacy in bone health and gastric acid neutralization.
Lab Monitoring
- Serum calcium levels (especially in patients with renal impairment or prolonged use)
- Serum phosphate levels
- Renal function tests
Doctor Notes
- Advise patients to take with food for better absorption.
- Remind patients about potential interactions with other medications, especially antibiotics and thyroid hormones.
- Monitor serum calcium levels in patients with risk factors for hypercalcemia or renal impairment.
Patient Guidelines
- Take with food to improve absorption.
- Drink plenty of water throughout the day.
- Inform your doctor about all other medications you are taking.
- Do not exceed the recommended dose.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Monocal 500 mg Tablet is not expected to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in calcium and Vitamin D.
- Engage in regular weight-bearing exercise to support bone health.
- Avoid excessive alcohol and caffeine consumption, which can affect calcium balance.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.