Moxichem
Generic Name
Moxifloxacin 0.5% Eye Drop
Manufacturer
Chemico Laboratories Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| moxichem 05 eye drop | ৳ 130.00 | N/A |
Description
Overview of the medicine
Moxichem-05 Eye Drop contains Moxifloxacin, a fourth-generation fluoroquinolone antibiotic, used to treat bacterial conjunctivitis and other susceptible ocular infections.
Uses & Indications
Dosage
Adults
Instill 1 drop into the affected eye(s) 3 times a day for 7 days.
Elderly
No dosage adjustment required.
Renal_impairment
No dosage adjustment required.
How to Take
For ophthalmic use only. Tilt head back, pull down lower eyelid to create a pouch, and instill the drop. Do not touch the dropper tip to any surface. Replace cap after use.
Mechanism of Action
Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, essential enzymes involved in bacterial DNA replication, transcription, repair, and recombination, leading to bacterial cell death.
Pharmacokinetics
Onset
Clinical improvement may be observed within a few days.
Excretion
Systemic excretion is renal and fecal, but minimal for topical ophthalmic use.
Half life
Approximately 13 hours in plasma after oral dose, but significantly less for topical ocular due to minimal systemic absorption.
Absorption
Minimal systemic absorption after topical ocular administration. Localized absorption within ocular tissues.
Metabolism
Systemic metabolism is hepatic, but minimal for topical ophthalmic use.
Side Effects
Contraindications
- Hypersensitivity to Moxifloxacin or other fluoroquinolones
- Hypersensitivity to any excipients in the formulation
Drug Interactions
Antacids
May reduce systemic absorption of oral Moxifloxacin; not relevant for topical ophthalmic.
Other Ophthalmic Drugs
If using multiple ophthalmic medications, administer them at least 5 minutes apart.
Storage
Store at room temperature (below 30°C). Protect from light. Do not freeze.
Overdose
Ocular overdose is unlikely to cause systemic toxicity due to minimal absorption. Rinse the eye with lukewarm water if excessive drops are applied.
Pregnancy & Lactation
Category C for pregnancy. Use only if potential benefit justifies the potential risk to the fetus. Caution advised during lactation as it is unknown if it is excreted in human milk after ocular administration.
Side Effects
Contraindications
- Hypersensitivity to Moxifloxacin or other fluoroquinolones
- Hypersensitivity to any excipients in the formulation
Drug Interactions
Antacids
May reduce systemic absorption of oral Moxifloxacin; not relevant for topical ophthalmic.
Other Ophthalmic Drugs
If using multiple ophthalmic medications, administer them at least 5 minutes apart.
Storage
Store at room temperature (below 30°C). Protect from light. Do not freeze.
Overdose
Ocular overdose is unlikely to cause systemic toxicity due to minimal absorption. Rinse the eye with lukewarm water if excessive drops are applied.
Pregnancy & Lactation
Category C for pregnancy. Use only if potential benefit justifies the potential risk to the fetus. Caution advised during lactation as it is unknown if it is excreted in human milk after ocular administration.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24 months. Discard 28 days after opening.
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA
Patent Status
Generic available
Clinical Trials
Extensive clinical trials support the efficacy and safety of Moxifloxacin ophthalmic solution for bacterial conjunctivitis. Data is available in various pharmaceutical databases and regulatory submissions.
Lab Monitoring
- No specific lab monitoring is required for topical ophthalmic Moxifloxacin.
Doctor Notes
- Advise patients on proper instillation technique to avoid contamination and maximize efficacy.
- Remind patients about the importance of completing the full course of therapy.
- Monitor for signs of allergic reactions or worsening infection.
Patient Guidelines
- Do not wear contact lenses during treatment for bacterial conjunctivitis.
- Avoid contaminating the dropper tip.
- Use for the full prescribed duration, even if symptoms improve.
- Consult a doctor if symptoms worsen or do not improve after a few days.
Missed Dose Advice
If a dose is missed, apply it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose.
Driving Precautions
May cause temporary blurred vision after instillation. Advise patients to avoid driving or operating machinery until vision clears.
Lifestyle Advice
- Maintain good eye hygiene.
- Avoid rubbing eyes.
- Wash hands thoroughly before and after applying eye drops.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.