Moxikem
Generic Name
Moxifloxacin
Manufacturer
Incepta Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| moxikem 05 eye drop | ৳ 100.30 | N/A |
Description
Overview of the medicine
Moxikem 0.5% Eye Drop contains Moxifloxacin, a fluoroquinolone antibiotic, used to treat bacterial infections of the eye, such as bacterial conjunctivitis.
Uses & Indications
Dosage
Adults
Instill one drop in the affected eye(s) 3 times a day for 7 days.
Elderly
No dosage adjustment is typically required for elderly patients.
Renal_impairment
No dosage adjustment is necessary for patients with renal impairment.
How to Take
For ophthalmic use only. Tilt your head back, pull down your lower eyelid to create a pouch, and instill one drop into the pouch. Close your eye gently for a few moments. Do not touch the dropper tip to your eye or any other surface.
Mechanism of Action
Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination, leading to bacterial cell death.
Pharmacokinetics
Onset
Rapid onset of antibacterial action, typically within hours.
Excretion
Mainly through feces and urine for systemically absorbed drug; ocular drug is cleared locally.
Half life
Ocular half-life is short, requiring frequent dosing. Systemic elimination half-life is approximately 13 hours.
Absorption
Following topical ocular administration, moxifloxacin is absorbed into the ocular tissues. Systemic absorption is minimal.
Metabolism
Minimal metabolism occurs in ocular tissues. Systemically absorbed drug is primarily metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to moxifloxacin, other quinolones, or any component of the medication.
Drug Interactions
Other topical ophthalmic medications
If more than one topical ophthalmic medication is being used, they should be administered at least 5 minutes apart.
Storage
Store below 30°C. Protect from light. Do not freeze. Keep out of reach of children.
Overdose
An ocular overdose is unlikely to cause systemic toxicity due to the limited absorption. In case of accidental ingestion or excessive ocular instillation, flush the eye with lukewarm water.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Exercise caution when administered to a nursing mother.
Side Effects
Contraindications
- Hypersensitivity to moxifloxacin, other quinolones, or any component of the medication.
Drug Interactions
Other topical ophthalmic medications
If more than one topical ophthalmic medication is being used, they should be administered at least 5 minutes apart.
Storage
Store below 30°C. Protect from light. Do not freeze. Keep out of reach of children.
Overdose
An ocular overdose is unlikely to cause systemic toxicity due to the limited absorption. In case of accidental ingestion or excessive ocular instillation, flush the eye with lukewarm water.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Exercise caution when administered to a nursing mother.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2 years unopened. 28 days after first opening.
Availability
Pharmacies
Approval Status
Approved
Patent Status
Generic available
Clinical Trials
Clinical trials have demonstrated the efficacy and safety of moxifloxacin ophthalmic solution in the treatment of bacterial conjunctivitis, showing significant bacterial eradication and clinical cure rates.
Lab Monitoring
- Not typically required for ophthalmic moxifloxacin.
Doctor Notes
- Advise patients on proper administration technique to ensure optimal drug delivery and minimize contamination.
- Emphasize the importance of completing the full prescribed course of treatment, even if symptoms improve, to prevent recurrence and resistance.
- Counsel patients to avoid wearing contact lenses during treatment for ocular bacterial infections.
Patient Guidelines
- Do not wear contact lenses during treatment with Moxikem eye drops. Remove contact lenses before instilling the drops and wait at least 15 minutes before reinserting them.
- Do not touch the dropper tip to your eye or any other surface to avoid contamination.
- Complete the full course of treatment as prescribed, even if your symptoms improve.
- Discard the bottle 28 days after opening.
Missed Dose Advice
If you miss a dose, instill it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not instill a double dose to make up for a missed one.
Driving Precautions
Moxikem eye drops may cause temporary blurring of vision or other visual disturbances. If this occurs, do not drive or operate machinery until your vision is clear.
Lifestyle Advice
- Practice good hand hygiene before and after instilling eye drops.
- Avoid rubbing your eyes.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.