Mycofree
Generic Name
Ketoconazole
Manufacturer
Acme Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| mycofree 1 cream | ৳ 100.00 | N/A |
| mycofree 250 mg tablet | ৳ 38.00 | ৳ 380.00 |
Description
Overview of the medicine
Mycofree Cream contains Ketoconazole, an antifungal agent used to treat various fungal skin infections such as ringworm, athlete's foot, jock itch, and seborrheic dermatitis.
Uses & Indications
Dosage
Adults
Apply to the affected and immediately surrounding areas once or twice daily. Continue treatment for a sufficient period, typically 2-4 weeks, until symptoms resolve and a few days thereafter to prevent recurrence.
Elderly
No special dosage adjustment required for elderly patients.
Renal_impairment
Not required for topical application.
How to Take
For topical use only. Clean and dry the affected area before applying a thin layer of cream. Rub gently until it is absorbed. Wash hands after application.
Mechanism of Action
Ketoconazole inhibits the biosynthesis of ergosterol, a vital component of fungal cell membranes. This leads to increased permeability and leakage of cellular contents, ultimately resulting in fungal cell death.
Pharmacokinetics
Onset
Symptom relief usually within a few days.
Excretion
Primarily local action; minimal excretion via systemic routes.
Half life
Not relevant for topical application due to minimal systemic absorption.
Absorption
Minimal systemic absorption when applied topically.
Metabolism
Negligible systemic metabolism when applied topically.
Side Effects
Contraindications
- Hypersensitivity to Ketoconazole or any component of the cream
- Systemic fungal infections (where topical treatment is insufficient)
Drug Interactions
0
No significant drug interactions are expected with topical application due to minimal systemic absorption.
1
However, caution is advised if used concomitantly with other topical products that may cause irritation.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause systemic effects. Excessive application may lead to skin irritation, erythema, or swelling. In case of accidental oral ingestion, supportive measures should be taken.
Pregnancy & Lactation
Pregnancy Category C. Use only if the potential benefit justifies the potential risk to the fetus. It is not known whether topical ketoconazole is excreted in human milk. Exercise caution when administered to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies nationwide
Approval Status
Approved
Patent Status
Expired
WHO Essential Medicine
YesClinical Trials
Ketoconazole has undergone numerous clinical trials demonstrating its efficacy and safety for various fungal infections since its introduction. Newer formulations or specific brand trials may exist.
Lab Monitoring
- No specific lab monitoring required for topical Ketoconazole use.
Doctor Notes
- Advise patients to complete the full course to prevent recurrence.
- Emphasize hygiene practices to avoid reinfection.
- Monitor for signs of local irritation or allergic reactions.
Patient Guidelines
- Use only as directed by a healthcare professional.
- Complete the full course of treatment, even if symptoms improve.
- Avoid contact with eyes and mucous membranes.
- Do not apply occlusive dressings over the treated area unless advised by a doctor.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply extra cream to make up for a missed dose.
Driving Precautions
No known effects on ability to drive or operate machinery for topical Ketoconazole.
Lifestyle Advice
- Keep the affected area clean and dry.
- Wear loose-fitting, breathable clothing.
- Avoid sharing towels, clothing, or personal items.
- Maintain good personal hygiene to prevent recurrence.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.