Mycofree
Generic Name
Clotrimazole
Manufacturer
Reputable pharmaceutical company
Country
Multiple countries
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| mycofree 1 cream | ৳ 100.00 | N/A |
Description
Overview of the medicine
Clotrimazole 1% cream is a topical antifungal medication used to treat a variety of fungal skin infections.
Uses & Indications
Dosage
Adults
Apply a thin layer to the affected area and surrounding skin twice daily, usually in the morning and evening, for 2-4 weeks.
Elderly
No specific dose adjustment required; same as adults.
Renal_impairment
No dose adjustment needed as systemic absorption is minimal.
How to Take
For external use only. Wash and dry the affected area before applying. Rub in gently until the cream disappears. Wash hands after application.
Mechanism of Action
Clotrimazole inhibits the biosynthesis of ergosterol, a vital component of fungal cell membranes, leading to increased cell permeability and eventual cell death.
Pharmacokinetics
Onset
Symptomatic relief often within a few days, full resolution may take weeks.
Excretion
Excreted via bile and urine, but negligible for topical use.
Half life
Not well characterized for topical application due to minimal systemic absorption.
Absorption
Poorly absorbed systemically after topical application.
Metabolism
Primarily metabolized in the liver if absorbed systemically, but negligible for topical use.
Side Effects
Contraindications
- Hypersensitivity to clotrimazole or any component of the cream.
Drug Interactions
Tacrolimus
Systemic absorption may increase tacrolimus levels, but minimal risk with topical clotrimazole.
Storage
Store below 30°C. Do not freeze. Keep out of reach of children.
Overdose
Overdose with topical clotrimazole is unlikely due to minimal systemic absorption. In case of accidental ingestion, seek medical advice.
Pregnancy & Lactation
Generally considered safe for topical use during pregnancy and lactation, but use with caution and under medical advice. Minimal systemic absorption.
Side Effects
Contraindications
- Hypersensitivity to clotrimazole or any component of the cream.
Drug Interactions
Tacrolimus
Systemic absorption may increase tacrolimus levels, but minimal risk with topical clotrimazole.
Storage
Store below 30°C. Do not freeze. Keep out of reach of children.
Overdose
Overdose with topical clotrimazole is unlikely due to minimal systemic absorption. In case of accidental ingestion, seek medical advice.
Pregnancy & Lactation
Generally considered safe for topical use during pregnancy and lactation, but use with caution and under medical advice. Minimal systemic absorption.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years when stored properly.
Availability
Pharmacies, drugstores, supermarkets
Approval Status
Approved by major regulatory bodies (e.g., FDA, DGDA)
Patent Status
Generic
WHO Essential Medicine
YesClinical Trials
Extensive clinical data supporting efficacy and safety for various fungal skin infections.
Lab Monitoring
- Generally not required for topical application.
Doctor Notes
- Emphasize patient compliance for full treatment course to prevent relapse.
- Advise patients on hygiene practices to prevent re-infection.
Patient Guidelines
- Complete the full course of treatment, even if symptoms improve.
- Avoid contact with eyes, nose, mouth, and other mucous membranes.
- Do not cover the treated area with an occlusive dressing unless advised by a doctor.
Missed Dose Advice
Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not apply extra cream to make up for a missed dose.
Driving Precautions
No known effects on ability to drive or operate machinery.
Lifestyle Advice
- Keep the affected area clean and dry.
- Wear loose-fitting, breathable clothing.
- Avoid sharing towels or personal items to prevent spreading infection.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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