Mylofen
Generic Name
Prednisolone
Manufacturer
Example Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| mylofen 5 mg tablet | ৳ 4.50 | ৳ 45.00 |
Description
Overview of the medicine
Mylofen 5 mg Tablet contains Prednisolone, a corticosteroid used to treat a wide variety of inflammatory and autoimmune conditions. It works by reducing inflammation and suppressing the immune system.
Uses & Indications
Dosage
Adults
Initial dose 5-60 mg daily, adjusted based on condition and patient response. Typically taken as a single daily dose or divided doses. For Mylofen 5mg, a common starting dose might be 5-10mg daily.
Elderly
Lower doses may be required due to increased sensitivity to side effects. Close monitoring is recommended.
Renal_impairment
No specific dose adjustment is usually required, but caution is advised in severe cases due to fluid retention.
How to Take
Take orally with food or milk to minimize gastrointestinal upset. Do not stop abruptly without consulting a doctor.
Mechanism of Action
Prednisolone acts as a glucocorticoid receptor agonist, modulating gene expression to reduce the synthesis of inflammatory mediators (prostaglandins, leukotrienes) and suppress the function of immune cells (lymphocytes, macrophages).
Pharmacokinetics
Onset
Anti-inflammatory effects typically begin within 1-2 hours after oral administration.
Excretion
Mainly excreted in the urine as inactive metabolites and unconjugated prednisolone.
Half life
Plasma half-life is 2-4 hours; biological half-life is 18-36 hours.
Absorption
Readily absorbed from the gastrointestinal tract, achieving peak plasma concentrations within 1-2 hours.
Metabolism
Primarily metabolized in the liver to inactive metabolites.
Side Effects
Contraindications
- Systemic fungal infections
- Known hypersensitivity to prednisolone or any component
- Live virus vaccines (while on immunosuppressive doses)
Drug Interactions
NSAIDs
Increased risk of gastrointestinal bleeding/ulceration.
Warfarin
Effects may be increased or decreased.
Diuretics
Increased potassium loss.
Antidiabetics
May reduce the effect of antidiabetic agents, requiring dose adjustment.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Acute overdose is rare. Symptoms may include fluid retention, hypertension, and glucose intolerance. Management is supportive and symptomatic.
Pregnancy & Lactation
Category C. Use only if potential benefit justifies the potential risk to the fetus. Prednisolone is excreted in breast milk; caution advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date
Availability
Available in pharmacies, hospitals, and clinics
Approval Status
Approved by major regulatory bodies (e.g., FDA, DGDA)
Patent Status
Generic available, original patent expired
WHO Essential Medicine
YesClinical Trials
Prednisolone has been extensively studied in numerous clinical trials for its efficacy in various inflammatory and autoimmune conditions.
Lab Monitoring
- Blood glucose levels (especially in diabetics)
- Electrolytes (potassium)
- Blood pressure
- Bone density (with long-term therapy)
Doctor Notes
- Emphasize gradual tapering of dosage.
- Monitor for signs of infection, hyperglycemia, and hypertension.
- Consider calcium and vitamin D supplementation for long-term users.
- Educate patients on potential mood changes and insomnia.
Patient Guidelines
- Do not stop the medication suddenly; tapering is required.
- Report any signs of infection immediately.
- Monitor blood sugar and blood pressure regularly.
- Avoid exposure to chickenpox or measles if not immune.
Missed Dose Advice
Take the missed dose as soon as you remember, unless it is almost time for your next dose. Do not double the dose.
Driving Precautions
Mylofen may cause dizziness or blurred vision in some individuals. Exercise caution when driving or operating machinery.
Lifestyle Advice
- Maintain a balanced diet rich in calcium and vitamin D.
- Engage in regular, moderate exercise.
- Limit sodium intake to reduce fluid retention.
- Avoid alcohol and smoking.
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.