Myoclop
Generic Name
Myoclop 75 mg Tablet
Manufacturer
MediCorp Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| myoclop 75 mg tablet | ৳ 10.00 | ৳ 100.00 |
Description
Overview of the medicine
Myoclop 75 mg Tablet is a hypothetical anticonvulsant medication primarily used for the management of myoclonus and certain types of seizures. It is believed to work by stabilizing electrical activity in the brain.
Uses & Indications
Dosage
Adults
Initial dose 75 mg once daily, may be increased up to 300 mg daily in divided doses based on response and tolerability.
Elderly
Start with a lower dose (e.g., 75 mg once daily) and titrate slowly due to potential for decreased renal clearance.
Renal_impairment
Dose adjustment required. For moderate impairment, reduce dose by 25-50%. Avoid in severe renal impairment.
How to Take
Take Myoclop 75 mg Tablet orally with a glass of water, with or without food. It is recommended to take it at the same time each day to maintain consistent drug levels.
Mechanism of Action
While the exact mechanism is hypothetical, Myoclop is thought to stabilize neuronal membranes and modulate neurotransmitter activity (e.g., GABAergic and glutamatergic systems) in the brain, reducing abnormal electrical discharges that cause myoclonus and seizures.
Pharmacokinetics
Onset
Within 1-2 hours
Excretion
Mainly excreted in urine, with a small portion excreted in feces.
Half life
Approximately 8-12 hours
Absorption
Rapidly absorbed from the gastrointestinal tract, with peak plasma concentrations reached within 1-3 hours.
Metabolism
Primarily metabolized in the liver, likely via oxidative pathways.
Side Effects
Contraindications
- Hypersensitivity to Myoclop or any excipients
- Severe hepatic impairment
- Acute narrow-angle glaucoma
Drug Interactions
Oral Contraceptives
Myoclop may reduce the efficacy of oral contraceptives.
Phenytoin, Carbamazepine
May alter Myoclop's metabolism, requiring dose adjustment.
Central Nervous System Depressants (e.g., alcohol, benzodiazepines)
May enhance CNS depressant effects, leading to increased sedation and drowsiness.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include severe drowsiness, dizziness, confusion, and possibly respiratory depression. Treatment is symptomatic and supportive, including gastric lavage if recent ingestion and monitoring vital signs.
Pregnancy & Lactation
Use in pregnancy only if potential benefit outweighs the risk to the fetus. Consult a doctor. Not recommended during breastfeeding as it may pass into breast milk.
Side Effects
Contraindications
- Hypersensitivity to Myoclop or any excipients
- Severe hepatic impairment
- Acute narrow-angle glaucoma
Drug Interactions
Oral Contraceptives
Myoclop may reduce the efficacy of oral contraceptives.
Phenytoin, Carbamazepine
May alter Myoclop's metabolism, requiring dose adjustment.
Central Nervous System Depressants (e.g., alcohol, benzodiazepines)
May enhance CNS depressant effects, leading to increased sedation and drowsiness.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include severe drowsiness, dizziness, confusion, and possibly respiratory depression. Treatment is symptomatic and supportive, including gastric lavage if recent ingestion and monitoring vital signs.
Pregnancy & Lactation
Use in pregnancy only if potential benefit outweighs the risk to the fetus. Consult a doctor. Not recommended during breastfeeding as it may pass into breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date
Availability
Pharmacies, Hospitals
Approval Status
Approved (Hypothetical)
Patent Status
Patent Pending (Hypothetical)
Clinical Trials
Clinical trials (hypothetical) demonstrated significant reduction in myoclonic jerks and seizure frequency compared to placebo, with a generally well-tolerated safety profile.
Lab Monitoring
- Baseline and periodic liver function tests
- Renal function monitoring (especially in elderly or renal impairment)
- Complete blood count (CBC) if long-term use
Doctor Notes
- Assess baseline liver and renal function before initiating therapy.
- Educate patients on potential CNS side effects and the importance of adherence.
- Gradual tapering is crucial upon discontinuation to avoid withdrawal symptoms.
Patient Guidelines
- Do not stop taking the medicine abruptly without consulting your doctor.
- Avoid driving or operating heavy machinery until you know how this medicine affects you.
- Report any unusual side effects or worsening of symptoms to your doctor immediately.
Missed Dose Advice
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Myoclop 75 mg Tablet may cause dizziness and drowsiness. Patients should be warned about driving or operating machinery until they are certain the medication does not impair their ability.
Lifestyle Advice
- Avoid alcohol consumption while on this medication as it may increase drowsiness.
- Maintain a regular sleep schedule and avoid activities that may trigger myoclonic jerks or seizures.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.