Mystrum
Generic Name
Nystatin
Manufacturer
Beximco Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| mystrum tablet | ৳ 4.83 | N/A |
Description
Overview of the medicine
Mystrum Tablet is an antifungal medication used to treat various fungal infections, particularly those caused by Candida species.
Uses & Indications
Dosage
Adults
500,000 to 1,000,000 units three times daily.
Elderly
Same as adult dosage, adjust based on patient's condition.
Renal_impairment
No specific dosage adjustment needed due to poor systemic absorption.
How to Take
Take orally with water, usually after meals. For oral candidiasis, allow tablet to dissolve slowly in the mouth, or crush and mix with water to gargle.
Mechanism of Action
Nystatin binds to sterols in the fungal cell membrane, leading to increased permeability and leakage of intracellular components, thereby causing cell death.
Pharmacokinetics
Onset
Local effect observed within 24-72 hours.
Excretion
Excreted largely unchanged in the feces.
Half life
Not significant due to poor systemic absorption.
Absorption
Poorly absorbed from the gastrointestinal tract; exerts local action.
Metabolism
Not significantly metabolized.
Side Effects
Contraindications
- Hypersensitivity to nystatin or any component of the formulation.
- Systemic fungal infections (Mystrum is for local action only).
Drug Interactions
Immunosuppressants (theoretical)
Theoretical concern with live fungal vaccines, but not direct interaction with Nystatin.
No significant drug interactions
No significant drug interactions reported for oral Nystatin due to poor systemic absorption.
Storage
Store in a cool, dry place, below 30°C, away from light and moisture. Keep out of reach of children.
Overdose
Overdose is unlikely due to poor absorption. Symptoms may include nausea, vomiting, and diarrhea. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe during pregnancy and lactation due to minimal systemic absorption. Consult a doctor before use.
Side Effects
Contraindications
- Hypersensitivity to nystatin or any component of the formulation.
- Systemic fungal infections (Mystrum is for local action only).
Drug Interactions
Immunosuppressants (theoretical)
Theoretical concern with live fungal vaccines, but not direct interaction with Nystatin.
No significant drug interactions
No significant drug interactions reported for oral Nystatin due to poor systemic absorption.
Storage
Store in a cool, dry place, below 30°C, away from light and moisture. Keep out of reach of children.
Overdose
Overdose is unlikely due to poor absorption. Symptoms may include nausea, vomiting, and diarrhea. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe during pregnancy and lactation due to minimal systemic absorption. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Expired
WHO Essential Medicine
YesClinical Trials
Extensively studied for local antifungal activity; further trials ongoing for broader applications.
Lab Monitoring
- No specific lab monitoring required for routine use.
Doctor Notes
- Emphasize local action and poor systemic absorption.
- Advise patients to complete the full course to prevent recurrence.
Patient Guidelines
- Complete the full course of treatment, even if symptoms improve.
- Do not share this medicine with others.
- If using for oral thrush, try to hold the dissolved tablet in your mouth for as long as possible before swallowing.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Mystrum tablet is not known to impair the ability to drive or operate machinery.
Lifestyle Advice
- Maintain good oral hygiene.
- Avoid excessive sugar intake, which can promote fungal growth.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.