Natrol
Generic Name
Natrol-005 Nasal Spray
Manufacturer
Fictional Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
Variant | Unit Price | Strip Price |
---|---|---|
natrol 005 nasal spray | ৳ 80.00 | N/A |
Description
Overview of the medicine
Natrol-005 Nasal Spray is used for the symptomatic relief of nasal congestion caused by colds, allergies, or sinusitis. It works by constricting blood vessels in the nasal passages.
Uses & Indications
Dosage
Adults
1-2 sprays into each nostril, 2-3 times daily, as needed. Do not use for more than 7 consecutive days.
Elderly
Same as adult dosage, with caution. Consult a physician for specific guidance.
Renal_impairment
No specific dosage adjustment is typically required due to minimal systemic absorption.
How to Take
Clear the nasal passages by blowing your nose. Tilt your head slightly forward, insert the nozzle into one nostril, and spray while gently inhaling. Repeat for the other nostril. Avoid swallowing the spray.
Mechanism of Action
Natrol-005 acts as an alpha-adrenergic agonist, causing vasoconstriction of the arterioles in the nasal mucosa. This reduces swelling and congestion, opening up the nasal passages.
Pharmacokinetics
Onset
Within 5-10 minutes.
Excretion
Systemically absorbed portion is primarily excreted renally.
Half life
Approximately 2-3 hours (local effect duration).
Absorption
Minimal systemic absorption through nasal mucosa; primarily acts locally.
Metabolism
Limited systemic metabolism due to minimal absorption.
Side Effects
Contraindications
- Hypersensitivity to the active ingredient or any excipients.
- Patients with narrow-angle glaucoma.
- Patients who have undergone transsphenoidal hypophysectomy or other surgery exposing the dura mater.
- Concurrent use with MAO inhibitors or within 14 days of stopping such treatment.
Drug Interactions
Tricyclic Antidepressants
May increase the risk of hypertension and arrhythmias when used with sympathomimetics.
Monoamine Oxidase Inhibitors (MAOIs)
Concurrent use may potentiate the pressor effects of Natrol-005, leading to severe hypertensive crisis. Avoid use within 14 days of stopping MAOI therapy.
Storage
Store below 30°C in a dry place, away from direct sunlight. Keep out of reach of children.
Overdose
Overdose may lead to local irritation, rebound congestion, or systemic effects such as headache, palpitation, or hypertension due to systemic absorption. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Use during pregnancy and lactation should only be considered if the potential benefit outweighs the potential risk to the fetus or infant. Consult a healthcare professional before use.
Side Effects
Contraindications
- Hypersensitivity to the active ingredient or any excipients.
- Patients with narrow-angle glaucoma.
- Patients who have undergone transsphenoidal hypophysectomy or other surgery exposing the dura mater.
- Concurrent use with MAO inhibitors or within 14 days of stopping such treatment.
Drug Interactions
Tricyclic Antidepressants
May increase the risk of hypertension and arrhythmias when used with sympathomimetics.
Monoamine Oxidase Inhibitors (MAOIs)
Concurrent use may potentiate the pressor effects of Natrol-005, leading to severe hypertensive crisis. Avoid use within 14 days of stopping MAOI therapy.
Storage
Store below 30°C in a dry place, away from direct sunlight. Keep out of reach of children.
Overdose
Overdose may lead to local irritation, rebound congestion, or systemic effects such as headache, palpitation, or hypertension due to systemic absorption. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Use during pregnancy and lactation should only be considered if the potential benefit outweighs the potential risk to the fetus or infant. Consult a healthcare professional before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
3 years from the manufacturing date.
Availability
Pharmacies, Superstores
Approval Status
Approved
Patent Status
Patent-free
Clinical Trials
Extensive clinical trials support the efficacy and safety of decongestant nasal sprays. Specific trials for Natrol-005 focus on its formulation and comparative effectiveness.
Lab Monitoring
- Routine laboratory monitoring is not typically required for Natrol-005 Nasal Spray.
Doctor Notes
- Advise patients on proper administration technique to ensure efficacy and minimize systemic absorption.
- Emphasize the importance of not exceeding 7 days of continuous use to prevent rhinitis medicamentosa.
- Counsel patients on potential interactions with MAOIs and tricyclic antidepressants.
Patient Guidelines
- Do not exceed the recommended dose.
- Do not use for more than 7 consecutive days to avoid rebound congestion.
- Avoid sharing the nasal spray device to prevent the spread of infection.
Missed Dose Advice
If you miss a dose, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for a missed one.
Driving Precautions
Natrol-005 Nasal Spray is not expected to affect the ability to drive or operate machinery. However, if you experience dizziness or visual disturbances, avoid such activities.
Lifestyle Advice
- Stay hydrated by drinking plenty of fluids.
- Avoid exposure to irritants like smoke and dust that can worsen nasal congestion.
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