Nazosol
Generic Name
Xylometazoline Hydrochloride + Sodium Chloride 0.9% w/v
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| nazosol 09 nasal drop | ৳ 25.00 | N/A |
Description
Overview of the medicine
Nazosol-09 Nasal Drop is used for the relief of nasal congestion caused by colds, allergies, and sinusitis. Xylometazoline acts as a decongestant, while Sodium Chloride helps to moisten the nasal passages and clear mucus.
Uses & Indications
Dosage
Adults
For adults and children over 12 years: 2-3 drops of 0.1% solution into each nostril 2-3 times daily, as needed. Do not use for more than 3-5 consecutive days.
Elderly
Same as adults, use with caution.
Renal_impairment
No specific dosage adjustment is generally required due to minimal systemic absorption.
How to Take
For nasal use only. Blow nose gently before use. Tilt head back, apply drops into each nostril, and keep head tilted for a few moments to allow the drops to spread.
Mechanism of Action
Xylometazoline is an alpha-adrenergic agonist that causes vasoconstriction of the nasal blood vessels, leading to a reduction in swelling and congestion of the nasal mucosa. Sodium Chloride helps to rehydrate the nasal passages and facilitate mucociliary clearance.
Pharmacokinetics
Onset
Within minutes
Excretion
Excreted renally if systemically absorbed.
Half life
Not well-defined for local action; systemic half-life (if absorbed) is approximately 6-8 hours.
Absorption
Minimal systemic absorption occurs following topical nasal administration. Primarily acts locally.
Metabolism
Any systemically absorbed xylometazoline is metabolized by the liver.
Side Effects
Contraindications
- •Hypersensitivity to xylometazoline or any component of the formulation
- •Patients who have undergone transsphenoidal hypophysectomy or surgery exposing the dura mater
- •Patients with angle-closure glaucoma
- •Patients with rhinitis sicca (dry inflammation of the nasal mucosa)
- •Children under 6 years for 0.1% solution
Drug Interactions
Tricyclic Antidepressants
May increase the risk of hypertension.
Monoamine Oxidase Inhibitors (MAOIs)
Concurrent use may lead to a hypertensive crisis. Avoid use within 14 days of MAOI therapy.
Storage
Store below 30°C. Protect from light and moisture. Do not freeze. Keep the bottle tightly closed.
Overdose
Symptoms of overdose may include severe CNS depression (especially in children), hypertension, tachycardia, or bradycardia. Treatment is symptomatic and supportive, including gastric lavage or activated charcoal if ingestion occurred.
Pregnancy & Lactation
Use with caution during pregnancy and lactation. Consult a doctor before use, as systemic absorption, though minimal, cannot be entirely excluded.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture. Use within 28 days after first opening.
Availability
Pharmacies, drugstores
Approval Status
Approved (OTC in many regions)
Patent Status
Generic
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Global Brand Names
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