Neto-B
Generic Name
Vitamin B Complex (containing Pyridoxine HCl 100mg, Thiamine HCl, Cyanocobalamin)
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| neto b 100 mg tablet | ৳ 9.00 | ৳ 90.00 |
Description
Overview of the medicine
Neto-B 100 mg tablet is a combination of essential B vitamins (B1, B6, B12) crucial for overall health. These vitamins play vital roles in energy metabolism, nerve function, and red blood cell formation. It is primarily used to prevent and treat B vitamin deficiencies and associated neurological conditions.
Uses & Indications
Dosage
Adults
Usually 1 tablet daily or as directed by the physician. In severe cases, dosage may be increased.
Elderly
No specific dosage adjustment required; use adult dosage.
Renal_impairment
No specific dosage adjustment required; use adult dosage.
How to Take
Take orally, preferably with or after food to minimize gastrointestinal discomfort.
Mechanism of Action
B vitamins act as coenzymes in numerous metabolic processes. Thiamine (B1) is essential for carbohydrate metabolism. Pyridoxine (B6) is involved in amino acid metabolism and neurotransmitter synthesis. Cyanocobalamin (B12) is vital for DNA synthesis, red blood cell formation, and neurological function.
Pharmacokinetics
Onset
Effects on metabolic processes can be observed within hours to days; symptomatic relief may take longer, especially for chronic deficiencies.
Excretion
Excess B vitamins, particularly water-soluble ones, are primarily excreted unchanged or as metabolites in the urine.
Half life
Thiamine: 9-18 days (tissue half-life); Pyridoxine: 15-20 days; Cyanocobalamin: Approximately 6 days.
Absorption
B vitamins are generally well absorbed from the gastrointestinal tract, primarily in the small intestine. Thiamine is absorbed by active transport and passive diffusion. Pyridoxine is absorbed rapidly. Cyanocobalamin requires intrinsic factor for absorption in the ileum.
Metabolism
B vitamins are metabolized in the liver to their active coenzyme forms.
Side Effects
Contraindications
- Known hypersensitivity to any component of the formulation.
- Leber's disease or other optic neuropathies (due to B12 component)
Drug Interactions
Levodopa
High doses of Pyridoxine (B6) may reduce the effectiveness of Levodopa (used in Parkinson's disease).
Phenobarbital/Phenytoin
High doses of Pyridoxine may decrease serum concentrations of these anticonvulsants.
Storage
Store in a cool, dry place (below 30°C), away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Acute overdose is rare and generally well-tolerated due to the water-soluble nature of B vitamins. However, very high doses of Pyridoxine (B6) over a prolonged period can lead to sensory neuropathy. Treatment is usually symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe in recommended doses during pregnancy and lactation, but consultation with a healthcare professional is advised before use.
Side Effects
Contraindications
- Known hypersensitivity to any component of the formulation.
- Leber's disease or other optic neuropathies (due to B12 component)
Drug Interactions
Levodopa
High doses of Pyridoxine (B6) may reduce the effectiveness of Levodopa (used in Parkinson's disease).
Phenobarbital/Phenytoin
High doses of Pyridoxine may decrease serum concentrations of these anticonvulsants.
Storage
Store in a cool, dry place (below 30°C), away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Acute overdose is rare and generally well-tolerated due to the water-soluble nature of B vitamins. However, very high doses of Pyridoxine (B6) over a prolonged period can lead to sensory neuropathy. Treatment is usually symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe in recommended doses during pregnancy and lactation, but consultation with a healthcare professional is advised before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from the date of manufacture.
Availability
Pharmacies, drugstores
Approval Status
Approved by DGDA
Patent Status
Generic
Clinical Trials
As a common vitamin supplement, extensive specific clinical trials for Neto-B as a brand are not typically published, but the efficacy of its active ingredients (B vitamins) is well-established through numerous studies.
Lab Monitoring
- Not routinely required for general supplementation. May be monitored in cases of suspected deficiency or malabsorption.
Doctor Notes
- Assess patients for specific B vitamin deficiencies before prescribing.
- Advise patients on lifestyle modifications to improve B vitamin status (diet, alcohol).
- Be aware of potential drug interactions, especially with Levodopa.
Patient Guidelines
- Take the tablet whole with water, do not crush or chew.
- Follow the prescribed dosage and duration.
- Inform your doctor about all other medications, supplements, or herbal products you are taking.
- Do not exceed the recommended dose without consulting a healthcare professional.
Missed Dose Advice
If a dose is missed, take it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose.
Driving Precautions
Neto-B is not known to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in fruits, vegetables, and whole grains.
- Avoid excessive alcohol consumption as it can impair B vitamin absorption.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.