Neumir
Generic Name
Desloratadine
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| neumir 5 mg tablet | ৳ 20.00 | ৳ 200.00 |
Description
Overview of the medicine
Neumir 5 mg Tablet contains Desloratadine, a non-drowsy antihistamine used to relieve allergy symptoms such as sneezing, runny nose, itchy eyes, and hives. It provides 24-hour relief without causing significant drowsiness.
Uses & Indications
Dosage
Adults
The recommended dose is 5 mg (one tablet) once daily, with or without food.
Elderly
No dosage adjustment is generally needed for elderly patients with normal renal and hepatic function.
Renal_impairment
For patients with severe renal impairment (creatinine clearance < 30 mL/min), a reduced frequency of 5 mg every other day is recommended.
How to Take
Neumir 5 mg Tablet should be taken orally, with or without food. Swallow the tablet whole with a glass of water. Do not crush or chew.
Mechanism of Action
Desloratadine is a long-acting tricyclic antihistamine with selective peripheral H1-receptor antagonist activity. It inhibits histamine release from mast cells and also inhibits the expression of adhesion molecules on endothelial cells, thereby reducing allergic inflammation.
Pharmacokinetics
Onset
Within 1 hour.
Excretion
Excreted almost equally in urine and feces as metabolic products.
Half life
Approximately 27 hours.
Absorption
Rapidly absorbed after oral administration; peak plasma concentrations reached in approximately 3 hours.
Metabolism
Extensively metabolized to 3-hydroxydesloratadine, an active metabolite, via hydroxylation followed by glucuronidation.
Side Effects
Contraindications
- Hypersensitivity to desloratadine, loratadine, or any component of the formulation.
- Children under 6 months of age.
Drug Interactions
Cimetidine
May increase plasma concentrations of desloratadine.
Fluoxetine
May increase plasma concentrations of desloratadine.
Azithromycin
No significant interaction reported.
Erythromycin
May increase plasma concentrations of desloratadine.
Ketoconazole
May increase plasma concentrations of desloratadine.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include drowsiness. In the event of an overdose, symptomatic and supportive treatment is recommended. Desloratadine is not eliminated by hemodialysis.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Desloratadine is excreted in breast milk; therefore, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date.
Availability
Available in pharmacies nationwide
Approval Status
Approved by regulatory authorities (e.g., FDA, DGDA)
Patent Status
Expired for generic Desloratadine
Clinical Trials
Desloratadine has undergone extensive clinical trials demonstrating its efficacy and safety for various allergic conditions, including seasonal and perennial allergic rhinitis and chronic idiopathic urticaria.
Lab Monitoring
- No specific routine lab monitoring is required. Liver function tests may be considered in patients with pre-existing hepatic impairment or if symptoms suggestive of liver dysfunction develop.
Doctor Notes
- Counsel patients on proper administration and potential side effects.
- Assess renal and hepatic function in patients with impairment.
- Avoid prescribing to patients with known hypersensitivity to desloratadine or loratadine.
Patient Guidelines
- Take this medicine exactly as prescribed by your doctor.
- Do not exceed the recommended dose.
- Inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements.
- If you experience any severe or persistent side effects, contact your doctor immediately.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at once to make up for a missed dose.
Driving Precautions
Desloratadine is generally considered non-drowsy. However, individuals may react differently. Exercise caution when driving or operating machinery until you know how this medicine affects you.
Lifestyle Advice
- Avoid known allergens that trigger your symptoms. Avoid alcohol while taking this medicine, as it may increase drowsiness.
- Maintain a healthy lifestyle to support overall well-being.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.