Neupomax
Generic Name
Pregabalin
Manufacturer
Beximco Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| neupomax 300 mcg injection | ৳ 2,700.00 | N/A |
Description
Overview of the medicine
Pregabalin is an anticonvulsant and neuropathic pain agent used to treat neuropathic pain, fibromyalgia, and as an adjunctive therapy for partial seizures.
Uses & Indications
Dosage
Adults
Initial 75 mg BID, max 300 mg BID (for most indications).
Elderly
Start with lower doses, adjust based on renal function.
Renal_impairment
Dose adjustment required based on creatinine clearance.
How to Take
Oral, with or without food.
Mechanism of Action
Binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of several neurotransmitters.
Pharmacokinetics
Onset
Varies by condition, often within a week for neuropathic pain.
Excretion
Primarily renal excretion of unchanged drug.
Half life
Approximately 6.3 hours.
Absorption
Rapidly absorbed, peak plasma concentrations within 1.5 hours.
Metabolism
Negligible metabolism.
Side Effects
Contraindications
- Hypersensitivity to pregabalin or any excipients.
Drug Interactions
Opioids
Increased CNS depression.
Benzodiazepines
Additive CNS depressant effects.
Storage
Store below 30°C, protected from light and moisture.
Overdose
Symptoms include somnolence, confusion, agitation. Management is supportive care.
Pregnancy & Lactation
Pregnancy Category C. Use only if benefits outweigh risks. Not recommended during lactation.
Side Effects
Contraindications
- Hypersensitivity to pregabalin or any excipients.
Drug Interactions
Opioids
Increased CNS depression.
Benzodiazepines
Additive CNS depressant effects.
Storage
Store below 30°C, protected from light and moisture.
Overdose
Symptoms include somnolence, confusion, agitation. Management is supportive care.
Pregnancy & Lactation
Pregnancy Category C. Use only if benefits outweigh risks. Not recommended during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months
Availability
Pharmacies, Hospitals
Approval Status
Approved by FDA/DGDA
Patent Status
Patent expired for generic versions
Clinical Trials
Extensive clinical trials for neuropathic pain, epilepsy, and fibromyalgia have been conducted.
Lab Monitoring
- No routine lab monitoring required.
Doctor Notes
- Monitor for CNS depression and suicidal ideation, especially during initial therapy or dose changes.
- Dose adjustment in renal impairment is crucial to avoid accumulation and adverse effects.
Patient Guidelines
- Do not stop abruptly without consulting a doctor.
- Report any unusual mood changes or suicidal thoughts.
- Avoid alcohol while taking this medicine.
- May cause dizziness or drowsiness, avoid driving or operating machinery.
Missed Dose Advice
Take as soon as remembered, but skip if close to next dose. Do not double dose.
Driving Precautions
May cause dizziness and drowsiness; avoid driving or operating machinery until effects are known.
Lifestyle Advice
- Maintain a healthy lifestyle.
- Regular exercise may help manage some symptoms.
- Practice stress management techniques.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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