Neurotonic
Generic Name
Thiamine Mononitrate + Pyridoxine Hydrochloride + Cyanocobalamin
Manufacturer
Acme Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| neurotonic 100 mg tablet | ৳ 5.00 | ৳ 50.00 |
Description
Overview of the medicine
Neurotonic-100 mg Tablet is a combination of B vitamins (Thiamine, Pyridoxine, Cyanocobalamin) used to support nerve health, metabolic processes, and treat vitamin B deficiencies.
Uses & Indications
Dosage
Adults
Typically 1-2 tablets daily, or as directed by a physician.
Elderly
No specific dose adjustment required; usual adult dose or as advised by physician.
Renal_impairment
No specific dose adjustment required, but caution with severe renal impairment.
How to Take
Take orally with water, preferably after meals to minimize gastrointestinal discomfort.
Mechanism of Action
Thiamine plays a crucial role in carbohydrate metabolism and nerve function. Pyridoxine is essential for amino acid metabolism and neurotransmitter synthesis. Cyanocobalamin is vital for DNA synthesis, red blood cell formation, and maintenance of myelin sheath around nerves.
Pharmacokinetics
Onset
Gradual, as it works to replenish deficiencies and support long-term nerve health.
Excretion
Primarily excreted via the kidneys in urine; excess water-soluble vitamins are readily eliminated.
Half life
Varies for each vitamin component: Thiamine (variable, up to 18 days with saturation), Pyridoxine (15-20 days), Cyanocobalamin (6 days to several months for tissue stores).
Absorption
Well absorbed orally, primarily from the small intestine.
Metabolism
Metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to any component of the formulation.
- Patients with Leber's disease (due to Cyanocobalamin)
Drug Interactions
Levodopa
Pyridoxine (Vitamin B6) may reduce the efficacy of Levodopa.
Certain Antibiotics
Some antibiotics (e.g., chloramphenicol) may interfere with Cyanocobalamin (Vitamin B12) absorption.
Storage
Store below 30°C in a cool, dry place. Protect from light and moisture.
Overdose
Overdose of water-soluble vitamins is rare due to rapid excretion. In case of accidental overdose, symptomatic and supportive measures should be taken.
Pregnancy & Lactation
Generally considered safe at recommended doses, but consult a doctor before use during pregnancy or lactation.
Side Effects
Contraindications
- Hypersensitivity to any component of the formulation.
- Patients with Leber's disease (due to Cyanocobalamin)
Drug Interactions
Levodopa
Pyridoxine (Vitamin B6) may reduce the efficacy of Levodopa.
Certain Antibiotics
Some antibiotics (e.g., chloramphenicol) may interfere with Cyanocobalamin (Vitamin B12) absorption.
Storage
Store below 30°C in a cool, dry place. Protect from light and moisture.
Overdose
Overdose of water-soluble vitamins is rare due to rapid excretion. In case of accidental overdose, symptomatic and supportive measures should be taken.
Pregnancy & Lactation
Generally considered safe at recommended doses, but consult a doctor before use during pregnancy or lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date.
Availability
Pharmacies, Drugstores
Approval Status
Approved by DGDA
Patent Status
Expired / Not Applicable
WHO Essential Medicine
YesClinical Trials
Clinical trials and extensive research support the efficacy of B vitamins in addressing neurological conditions and deficiencies. Specific trials for Neurotonic-100 mg may be available from the manufacturer.
Lab Monitoring
- Not routinely required for general use.
- Monitor B vitamin levels if deficiency is suspected or for specific medical conditions.
Doctor Notes
- Neurotonic-100 mg Tablet is a useful adjunctive therapy for various neuropathic conditions, particularly those associated with vitamin B deficiencies.
- Educate patients on the importance of adherence to dosage and potential interactions with Levodopa.
Patient Guidelines
- Follow your doctor's or pharmacist's instructions.
- Do not exceed the recommended daily dose.
- Keep out of reach of children.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Neurotonic-100 mg Tablet is not known to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in essential nutrients.
- Engage in regular physical activity and manage stress for overall well-being.
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