Nomos
Generic Name
Omeprazole
Manufacturer
Acme Laboratories Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| nomos 125 cream | ৳ 120.00 | N/A |
Description
Overview of the medicine
Nomos (Omeprazole) is a proton pump inhibitor used to treat conditions caused by excess stomach acid, such as heartburn, gastroesophageal reflux disease (GERD), and ulcers.
Uses & Indications
Dosage
Adults
Usually 20 mg once daily for 4-8 weeks, or 40 mg once daily for severe cases. For H. pylori eradication, 20 mg twice daily with antibiotics.
Elderly
No dose adjustment generally required, but caution in severe hepatic impairment.
Renal_impairment
No dose adjustment required.
How to Take
Take orally, preferably in the morning before a meal. Swallow the capsule whole; do not chew or crush.
Mechanism of Action
Omeprazole works by irreversibly binding to and inhibiting the H+/K+-ATPase (proton pump) in gastric parietal cells, thereby reducing gastric acid secretion.
Pharmacokinetics
Onset
Within 1 hour
Excretion
Mainly through urine (approx. 80%) and feces (approx. 20%).
Half life
Approximately 0.5-1 hour
Absorption
Rapidly absorbed, bioavailability approximately 30-40% due to first-pass metabolism.
Metabolism
Extensively metabolized in the liver by CYP2C19 and CYP3A4.
Side Effects
Contraindications
- Hypersensitivity to Omeprazole or other benzimidazoles
- Concomitant use with Nelfinavir
Drug Interactions
Warfarin
Increased INR/bleeding risk.
Clopidogrel
Reduced antiplatelet effect of clopidogrel (CYP2C19 inhibition).
Storage
Store below 30°C in a dry place, away from light and moisture.
Overdose
Symptoms include nausea, vomiting, dizziness, abdominal pain, diarrhea, and headache. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Category C in pregnancy. Use only if clearly needed. Excreted in breast milk, use with caution.
Side Effects
Contraindications
- Hypersensitivity to Omeprazole or other benzimidazoles
- Concomitant use with Nelfinavir
Drug Interactions
Warfarin
Increased INR/bleeding risk.
Clopidogrel
Reduced antiplatelet effect of clopidogrel (CYP2C19 inhibition).
Storage
Store below 30°C in a dry place, away from light and moisture.
Overdose
Symptoms include nausea, vomiting, dizziness, abdominal pain, diarrhea, and headache. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Category C in pregnancy. Use only if clearly needed. Excreted in breast milk, use with caution.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Available in pharmacies nationwide
Approval Status
Approved by FDA and DGDA
Patent Status
Generic available, original patent expired
WHO Essential Medicine
YesClinical Trials
Numerous clinical trials confirm efficacy and safety in various acid-related disorders.
Lab Monitoring
- Magnesium levels (long-term use)
- Chromogranin A (CgA) for neuroendocrine tumors
Doctor Notes
- Consider lowest effective dose for shortest duration.
- Monitor for bone health and magnesium levels in chronic users.
- Evaluate for underlying cause of symptoms before starting PPIs.
Patient Guidelines
- Take as directed by your doctor.
- Do not stop taking the medicine suddenly.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not double the dose.
Driving Precautions
May cause dizziness or visual disturbances. Exercise caution.
Lifestyle Advice
- Avoid spicy and fatty foods.
- Eat small, frequent meals.
- Elevate the head of your bed to reduce reflux symptoms.
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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